绒癌脑转移的神经外科治疗  

Neurosurgery for Brain Metastases of Choriocarcinomas

作　　者：廖可立[1] 王汉东[1] 谢韡[1] 潘云曦[1] 乔梁[1] 

机构地区：[1]南京军区南京总医院神经外科,江苏南京210002

出　　处：《中国临床神经外科杂志》2008年第5期266-268,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的探讨绒癌脑转移神经外科诊断、治疗原则及手术方法。方法回顾性分析1995年1月至2007年1月间在我院确诊为绒癌脑转移而行神经外科手术治疗的21例患者的临床资料,其中19例术后接受了联合方案化疗。结果21例绒癌脑转移患者中,术后症状完全缓解11例,部分缓解8例,死亡2例。其中14例随访1～10年,存活11例,死亡3例;失访5例。结论对于绒癌脑转移患者,早期诊断与及时有效的化疗是改善预后的关键,积极的神经外科手术是挽救患者生命,获得进一步化疗机会的重要方法。Objective To study the diagnosis and treatment of brain metastasis of choriocarcinomas. Methods The clinical data of 21 patients with brain metastases of choriocarcinmas, who underwent surgery and were treated by chemotherapy in our hospital from January, 1994 to January, 2007, were analyzed retrospectively. Results Of 21 patients with brain metastases of choriocarcinomas, 11 achieved complete remission, 8 partial remission, and 2 died. Of 14 followed up from 1 to 10 years, 11 survived and 3 died. Conclusions The prognoses are bad in the patients with intracranial metastases of choriocarcinomas. Early diagnosis and chemotherapy play the key role in the management of the patients with brain metastases of choriocarcinoma and neurosurgery also is the important method to treat them.

关 键 词：绒癌 脑转移 神经外科手术 化疗 

分 类 号：R739.41[医药卫生—肿瘤] R737.33[医药卫生—临床医学]