醋酸肉眼观察用于宫颈病变筛查的价值  

The value of visual inspection of the cervix with acetic acid for screening cervical intraepithelial lesions

作　　者：孟君艳[1] 李筠[1] 游建群 张筠[1] 

机构地区：[1]北京航天总医院妇产科,100076

出　　处：《中国现代医药杂志》2008年第5期47-49,共3页Modern Medicine Journal of China

摘　　要：目的研究醋酸肉眼观察用于宫颈病变筛查的价值。方法600名妇女依次接受液基细胞学检测(TCT),醋酸肉眼观察,阴道镜检查并取活检,将醋酸肉眼观察结果与宫颈细胞学检查结果进行比较。结果醋酸肉眼观察的灵敏度为82.8%(77/93),高于TCT(72.0%),尤其是对于CIN2级以上的病变灵敏度可达91.4%(32/35),阳性预测值67.8%,阴性预测值97.9%。醋酸肉眼观察特异性为92.7%(470/507),与TCT(92.5%)相近。结论醋酸肉眼观察法是检查宫颈阴道部病变的一种非常灵敏的肉眼检查方法,便宜且操作简单,灵敏度高且迅速出结果,尤其适用于贫困地区、一些基层卫生院及进行宫颈癌的普查,对于那些拒绝TCT等检查者,也可用此方法进行初筛。Objective To access the value of visual inspection of the cervix with acetic acid （VIA） for cervical intraepithelial lesions. Methods 600 women were screened using TCT,VIA,colposcopy and biopthy under colposcopy. Compare the result of VIA with TCT. Results The sensitivity of visual inspection with acetic acid （82.8%）was higher then that of TCT（72.0%）,especially the sensitivity of visual inspection for CIN 2 and worse lesions（91.4%）,positive predictive value was 67.8%,negative predictive value was 97.9%.The specificity of VIA （92.5%）was similar with that of TCT（92.7%）. Conclusion Visual inspection of the cervix with acetic acid （VIA） is a sensitive method for ectocervical lesions. And it has many advantages like its low costs,easy to use,high sensitivity and its immediate results. Especially suitable for cervical cancer screening in low-resource settings. It also can be used for the patients who refuse to do TCT for some reason.

关 键 词：醋酸 肉眼观察 筛查 宫颈上皮内病变 

分 类 号：R737.33[医药卫生—肿瘤] R711.74[医药卫生—临床医学]