N-(4-苯基-噻唑-2-基)芳醛腙类化合物的合成  

Synthesis of N-(4-Phenylthiazol-2-yl)aromatic Aldehyde Hydrazones

作　　者：刘玮炜[1] 赵跃强[1] 王钦琪[1] 李娜[1] 唐丽娟[1] 曾艳霞[1] 

机构地区：[1]淮海工学院化工系,连云港222005

出　　处：《有机化学》2008年第5期907-909,共3页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20672090);江苏省教育厅自然科学基金(No.06KJD150015);江苏省海洋生物技术重点建设实验室基金(No.2006HS014);江苏省"六大人才高峰"(No.07-A-024)资助项目

摘　　要：以芳醛与氨基硫脲进行缩合得到缩氨基硫脲,分别与ω-溴苯乙酮进行成环反应得到了一系列含噻唑环和芳基的腙类化合物,并通过用1H NMR、质谱、红外光谱等对化合物进行了结构表征.A series of aromatic aldehyde hydrazones including the 2-thiazolyl unit have been designed and synthesized by the cyclization of thiosemicarbazones with ω-bromoacetophenone, in which thiosemicarbazones were prepared by the condensation reaction of aromatic aldehyde with thiosemicarbazide. The structures of the products were established by IR, ^1H NMR and MS spectra.

关 键 词：缩氨基硫脲 N-(4-苯基-噻唑-2-基)芳醛腙类化合物 合成 

分 类 号：TQ460.1[化学工程—制药化工]