进展性卒中的临床分析  

Clinical analysis of patients with stroke in progression

作　　者：贾丽君[1] 迟鲁梅[2] 范佳[3] 刘群[1] 

机构地区：[1]吉林大学第一医院神经内科,吉林长春130021 [2]吉林大学中日联谊医院神经内科,吉林长春130031 [3]吉林大学第二医院神经内科,吉林长春130041

出　　处：《中风与神经疾病杂志》2008年第2期191-193,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的深入探讨进展性卒中的临床特点、病因及意义。方法将发病24h内入院治疗的153例脑梗死患者进行分组,观察进展性卒中患者的临床表现,并将其血压、血糖、血脂、纤维蛋白原、梗死部位、脑彩超、颈部彩超结果与非进展组进行比较。结果进展性卒中神经功能缺失症状加重以24h内最常见,高血压和糖尿病是进展性卒中的重要病因,纤维蛋白原增高,梗死部位及血管狭窄程度是进展性卒中发生的一个重要原因。结论针对可引起进展性卒中的危险因素进行积极干预可有效抑制其发生。Objective To explore the etiology, clinical manifestations, diagnosis, as well as the treatment program and enhance the recognition to stroke in progression. Methods We performed retrospective analysis on the original data of the 153 cerebral infarction patients who presented within 24 hours of onset. A total of 153 patients were diagnosed as stroke in progression（SIP）and non-progression stroke group（NPS） according to their decrease scores in Scandinavian stroke scale （SSS） from baseline to the 1-week evaluation. The SIP and NPS stroke patients were compared in terms of their background characteristics, blood pressure, blood glucose, cholesterol, fibrinogen, cranial CT and TCD. Results The overall incidence of SIP was 34.64%. Hypertension and hyperglycemia differed significantly between SIP group and NPS group. Higher FIB and the infarct region were important factors of worsening. The infarct in watershed, besides body of lateral ventricle and large volume infarction were more common in SIP. Stenosis, especially the medium or severe stenosis of the MCA, extracranial section of the internal carotid artery was an important risk factor for SIP. Conclusion The difference between SIP group and NPS group were significant. We should pay attention to the cerebral infarction patients who presented within 24 hours of onset probably. Cranial CT and TCD examination were essential. We should adopt effective method to prevent and cure the risk factors to lead to SIP.

关 键 词：进展性卒中 临床特点 病因 

分 类 号：R743.1[医药卫生—神经病学与精神病学]