眩晕宁对颈性眩晕患者血浆内皮素水平的影响及其意义  

Effect of Xuanyunning on plasma endothelin level in patients with cervical vertigo

作　　者：季燕[1] 

机构地区：[1]武警河南总队医院神经内科,河南省郑州市450052

出　　处：《国际神经病学神经外科学杂志》2008年第2期118-120,共3页Journal of International Neurology and Neurosurgery

摘　　要：目的观察眩晕宁对颈性眩晕患者血浆内皮素水平的影响,并探讨其作用机制。方法将93例颈性眩晕患者分为眩晕宁治疗组52例和非眩晕宁治疗组(对照组)41例,分别检测两组研究对象治疗前后血浆内皮素值,并对其眩晕症状改善程度进行评价。结果眩晕宁治疗组治疗后血浆内皮素水平较治疗前明显下降(P<0.05),且明显低于对照组(P<0.05);眩晕宁治疗组的总有效率为90.4%,高于对照组的73.2%(P<0.05)。结论眩晕宁可明显降低颈性眩晕患者的血浆内皮素水平,改善其临床症状。Objective To study the effect of Xuanyunning on plasma endothelin level in patients with cervical vertigo and possible mechanisms underlying the effect of Xuanyunning on cervical vertigo. Methods Ninety-three patients with cervical veritigo were randomly assigned to Xuanyunning therapy （n = 52） and control groups （n = 41 ）. After treatment, plasma endothelin level was detected and clinical symptoms were observed. Results After treatment, plasma endothelin level in the Xuanyunning therapy group was significantly reduced （ P 〈 0.05 ） and lower than that in the control group （ P 〈 0.05 ）. The total effective rate in the Xuanyunning therapy group was Significantly higher than that in the control group （90.4% vs 73.2% ; P 〈 0.05）. Conclusions Xuanyunning can decrease plasma endothelin level and thus improves clinical symptoms in patients with cervical vertigo.

关 键 词：颈性眩晕 眩晕宁 内皮素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]