爱肌松临床应用的监测  

Relaxation of Alloferin Used in Man

作　　者：宋晓阳 岳云[1,2] 

机构地区：[1]西安市军工医院麻醉科 [2]第四军医大学唐都医院麻醉科

出　　处：《临床麻醉学杂志》1997年第4期209-210,共2页Journal of Clinical Anesthesiology

摘　　要：用连续四次刺激法持续监测２０例患者（ＡＳＡⅠ～Ⅱ级）在静脉复合和静吸复合全麻（随机分成相应两组）下的肌松效应。结果：爱肌松（２５０μｇ／ｋｇ）起效时间２．９５±１．５４ｍｉｎ，达到插管时间５．２１±１．３７ｍｉｎ（部分病人尚存在声门活跃）。维持用诱导量的１４可得到３２～８０ｍｉｎ满意肌松。反复追加蓄积作用不明显。呼吸恢复较迅速。当Ｔ１＜２５％时，６０％以上患者出现自主呼吸，表明该药在呼吸肌和其他横纹肌麻痹之间存在相对的差异。The relaxation of alloferin was monitored with TOF stimulation in 20 surgical patients under general anesthesia. The onset time of alloferin in a dose of 250μg/kg was 2 95±1 54min. The time from injection to intubation was 5 21±1 37min. The satisfectory relaxation could be maintained for 32 to 80 min by a supplementary injection of a quarter intubation dose of alloferin. There was no any remarkable cumulative relaxation when used repeatedly. No prolonged respiratory depression was found.Spontaneous respiration appeared in 60% of the patients in whom T 1 was less than 25%, indicating that a relative difference is present between the respiratory muscles and the other skeletal muscle.

关 键 词：爱肌松 神经肌肉阻滞 监测 静脉麻醉 复合麻醉 

分 类 号：R614.2[医药卫生—麻醉学] R971.8[医药卫生—外科学]