复方甘草酸苷治疗酒精性肝炎临床疗效观察  

Compound glycyrrhizin for alcoholic hepatitis：observation of clinical efficacy

作　　者：董晓艳[1] 

机构地区：[1]齐齐哈尔医学院附属第三医院医务科,黑龙江省齐齐哈尔161000

出　　处：《中国基层医药》2008年第4期602-603,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察复方甘草酸苷治疗酒精性肝炎的临床疗效。方法对照组30例，戒酒，运动，调整饮食。治疗组35例，在对照组基础上加用复方甘草酸苷片。4周为1个疗程，共3个疗程。治疗前后分别测定肝功能及肝脏B型超声波检查。结果治疗组临床症状明显减轻，血清ALT、AST、GGT水平降低，治疗组明显优于对照组（P〈0．05）。肝脏B超显示脂肪肝影像明显改善或消失。结论复方甘草酸苷治疗酒精性肝炎可以明显改善患者的临床症状和肝功能。Objective To observe the therapeutic effect of compound glycyrrhizin on alcoholic hepatitis. Methods A total of 65 patients with alcoholic hepatitis were assigned to group A（30 cases） treated with abstinence of alcohol,physical exercise and adjusted diet, and group B（35 cases） treated with compound glycyrrhizin together with the treatment given to group A. Before and after receiving three 4-week treatment periods,all the patients had their liver function tested and received examination of ultrasonic weave type B. Results Group B had significantly alleviated clinical symptoms, and ACT, AST, GGT in blood serum are significantly lower than group A（P 〈 0.05）. Examination of ultrasonic wave type B on the liver shows significant amelioration and disappearance of symptoms of fatty liver. Conclusion Compound glycyrrhizin can significantly ameliorate the clinical symptoms and improve the liver function of the patients.

关 键 词：肝炎 酒精性 甘草酸 

分 类 号：R575[医药卫生—消化系统]