表兄链球菌致龋性与免疫防龋的研究进展  

Advances on the cariogenic character of Streptococcus sobrinus and its relationship with anti-caries immunization

作　　者：孙静华[1] 牛玉梅[1] 樊明文[2] 

机构地区：[1]哈尔滨医科大学口腔医院牙体牙髓病科,黑龙江哈尔滨150001 [2]口腔生物医学工程教育部重点实验室,武汉大学,湖北武汉430079

出　　处：《国际口腔医学杂志》2008年第2期167-169,175,共4页International Journal of Stomatology

基　　金：国家自然科学基金资助项目(30672325)

摘　　要：表兄链球菌是变异链球菌群中的一种重要致龋菌,检出率逐渐提高。与变异链球菌相比较,表兄链球菌的产酸性和耐酸性更强,与高度龋活性的关系更为密切,日益引起学者们的重视。下面就该菌的致龋性及其与免疫防龋相关的研究进展作一综述,以期对龋病病因学和免疫防龋的深入研究提供参考。Streptococcus sobrinus LS.sobrinus） is another important cariogenic microorganism of Mutans streptococci（S.mutans）. Although S.sobrinus was less frequently detected in human oral cavities than S.mutans, it has been described as more virulent than S.mutans due to its high acidogenicity and acid tolerance. Following the improvement of test facility and the elevation of detection sensibility, the detection rate of S.sobrinus in human oral has been rising obviously. The study about S.sobrinus has progressed markedly in the last two decades, and we provide a summary of advances on the bionomics, cariogenic character of S.sobrinus and its relationship with anti-caries immunization, in order to provide some reference for further study about etiology of dental caries and anti-caries immunization.

关 键 词：表兄链球菌 检出率 致龋性 免疫防龋 

分 类 号：R781.1[医药卫生—口腔医学]