膀胱癌肉瘤诊治2例报告并文献复习  

Carcinosarcoma of the urinary bladder:a report of 2 cases with literature review

作　　者：王乐浩 李星洪[1] 李光昭[1] 

机构地区：[1]广东省汕头市第二人民医院泌尿外科,515041

出　　处：《中国实用医药》2008年第14期30-31,共2页China Practical Medicine

摘　　要：目的结合文献复习,提高膀胱癌肉瘤的诊治水平。方法回顾分析2例膀胱癌肉瘤患者的临床和病理资料。男女各1例,均以无痛性肉眼血尿为主要症状,B超或CT提示膀胱占位,膀胱镜下见膀胱内肿物,活检病理2例均提示移行细胞癌。结果2例均行膀胱部分切除,术后病理均为膀胱癌肉瘤,显微镜下主要由高分化移行细胞癌和肉瘤成分组成。免疫组化显示:CK及Vimen-tin反应均为阳性。结论诊断依赖病理及免疫组化检查,治疗以根治性手术为主,预后不良。Objective To review the literature of carcinosarcoma of the urinary bladder,in order to increase level of the diagnosis and treatment.Methods 2 cases of carcinosarcoma（one man and one woman） were included.They were admitted to hospital with painless,macroscopic hematuria.Clinic opathalogic features of all findings of the 2 cases were reviewed.All the B-ultrasonic and CT examination of the bladder were confirmed the presence of parenchymatous tumors.Cystoscopy of both cases showed the tumor in the bladder.Pathology of 2 cases showed transitional cell carcinoma.Results Partial cystectomy was performed in 2 patients.Postoperative pathology of 2 cases showed carcinosarcoma.Microscopically,the tumors composed mostly of high grade transitional cell carcinoma mixed with sarcomatous components.Immunohistochemically,all tumors were positive for CK and Vimentin.Conclusion Diagnosis of carcinosarcoma depends on the pathology and immunohistochemically.The patients should be treatment with radical operation.Carcinosarcoma of the urinary bladder has an unfavorable prognosis.

关 键 词：膀胱肿瘤 膀胱癌肉瘤 临床分析 治疗方法 

分 类 号：R737.14[医药卫生—肿瘤]