胸腔灌注化疗联合全身化疗治疗乳腺癌恶性胸水35例疗效分析  

The therapeutic effect of thirty-five breast cancer patients with malignant pleural fluid by thoracic cavity and systematic chemotherapy

作　　者：蔡君 叶青青 李晶晶 柯庆华 边耀武 李洪涛 蒋代文 杨继元 

机构地区：[1]荆州市肿瘤医院肿瘤科,湖北荆州434007

出　　处：《现代肿瘤医学》2008年第6期975-976,共2页Journal of Modern Oncology

摘　　要：目的:观察采用一次性中心静脉导管胸腔闭式引流后,胸腔内局部灌注化疗联合全身化疗治疗乳腺癌大量胸腔积液的疗效。方法:在常规全身化疗的基础上,胸腔闭式引流完胸水后,通过导管在胸腔内注射博来霉素。结果:胸腔积液控制的有效率77.14%,毒副作用主要是骨髓抑制、消化道反应。结论:乳腺癌伴大量胸腔积液,常规化疗的同时,通过胸腔闭式引流管局部注射博来霉素,方法简单有效。Objective：To observe the curative effect of bleomycin regional perfusion into thoracic cavity after thoracic close drainage, associating systematic chemotherapy in breast carcinoma patients with generous hydrothorax. Methods： On the base of conventional systematic chemotherapy, the breast carcinoma patients were administrated thoracic close drainage to eliminate hydrothorax, and then perfused bleomycin into thoracic cavity through the central venous catheter . Results： The effective ratex of hydrothorax control was 77.14%, the main side effect was myelosuppression and alimentary canal response. Conclusion： Generous hydrothorax from breast carcinoma patients could be effectively controlled by perfused bleomycin into thoracic cavity through the central venous catheter base on con- ventional systematic chemotherapy ,and the therapeusis was simple.

关 键 词：乳腺肿瘤 胸腔积液 局部灌注 

分 类 号：R737.9[医药卫生—肿瘤]