正常人房水闪辉和细胞的定量测量  

Quantitative determination of aqueous flare and cells in healthy eyes

作　　者：王红[1] 周增超[1] 魏文斌[1] 梁亮[1] 侯彬[1] 陈海婷[1] 

机构地区：[1]首都医科大学附属北京同仁医院眼科中心,100730

出　　处：《眼科》2008年第3期201-204,共4页Ophthalmology in China

基　　金：国家自然科学基金资助项目(30772013)

摘　　要：目的测量正常人的房水闪辉和细胞数量,观察年龄和性别对血-房水屏障的影响。设计前瞻性病例系列研究。研究对象221例正常人(442眼)。方法采用FC-2000型激光蛋白细胞检测仪(LFCM)非接触、定量地检测了221例正常人(442眼)的房水闪辉和细胞。主要指标房水闪辉和细胞。结果正常人的房水闪辉平均值为(4.7±2.9)pc/ms,其中<10岁为(3.1±1.O)pc/ ms,40-49岁组为(3.8±1.9)pc/ms,≥80岁者达到(11.0±4.8)pc/ms。与40～49岁组相比,50岁以上各年龄组的房水闪辉值均显著增高(P均<0.05),男性与女性之间无显著差异(P=0.686),左右眼之间无显著差异(P=0.512)。正常人房水细胞平均值为(0.4±0.7)个,与40～49岁年龄组相比,80岁以上者房水细胞值显著增高(P=0.014),男性与女性之间无显著差异(P=0.413),左右眼之间无显著差异(P=0.886)。结论LFCM可定量检测房水闪辉值并了解蛋白浓度和细胞数量,此项检查对定量检测血-房水屏障的改变和前房炎症具有重要意义。Objective To quantify aqueous flare and cells in the eyes of healthy subjects and to evaluate the effect of age and sex on the blood aqueous barrier. Design Prospective case series. Participants Four hundred and forty-two eyes of 221 healthy subjects. Methods Aqueous flare and cells of 442 eyes were evaluated with FC-2000 laser flare cell meter （LFCM）. Main Outcome Measures Aqueous flare and cells. Results The mean flare values of all of eyes was 4.7±2.9 pc/ms, it was 3.1 pc/ms in the age group of less than 10 years, 3.8 pc/ms in the age group of 40-49 years and 11.0 pc/ms in the age group of 80 years or over. The mean flare values in the age groups of 50 years or over were significantly higher than that in the age group of 40-49 years （P〈0.05）. There were no significant differences in the mean flare values between sex groups （P=0.686）, or between right and left eyes （P=0.512）.The mean cell count was 0.4±0.7. The mean cell count in the age group of 80 years or over was higher than that in the age group of 40-49 years （P〈 0.05）. There were no significant changes in the mean cell between sex groups （P=0.413）, or between right and left eyes （P=0.886）. Conclusions LFCM can give accurate data on the flare and cell counts in the aqueous humour, and it can be used to quantitate the changes in the blood aqueous barrier and inflammation in the aqueous humour.

关 键 词：房水闪辉 房水细胞 激光蛋白细胞检测仪 

分 类 号：R77[医药卫生—眼科]