可吸收复合壳聚糖引导药膜的研究  

Study on the Absorbable Guided Chitosan Medicine Membrane

作　　者：董陈[1] 徐靖宏[1] 蔡镭[2] 胡巧玲[2] 林军[1] 

机构地区：[1]浙江大学附属第一医院,浙江杭州310003 [2]浙江大学材化学院高分子系,浙江杭州310027

出　　处：《稀有金属材料与工程》2008年第A02期678-681,共4页Rare Metal Materials and Engineering

摘　　要：以为引导牙周组织再生术(GTR)工程制备性能优越的可吸收壳聚糖生物引导药膜为目的,选用壳聚糖膜作为载体,加入不同量的改良的冰硼散中药,利用流延法制备不同含药质量比的引导膜,并测试其力学性能。结果表明:除含药质量比为壳聚糖?冰硼散=100?10.5及100?21时成膜力学性能相对较差外,其余研制的药物质量比可吸收壳聚糖引导药膜的机械性能较好。从材料的机械性能看,壳聚糖药膜基本符合引导组织再生膜的要求。This paper reports a new absorbable guided chitosan medicine membrane which could be used for guided tissue regeneration （GTR）. With chitosans carrying different amount of Chinese traditional medicine, different medicine membranes were prepared. Their biomechanics performances were also examined. Except membranes group No. 3 and No. 5, other membranes showed good mechanical strength. From these results, it is concluded that these membranes meet the requirements of guided tissue regeneration.

关 键 词：壳聚糖膜 冰硼散 冰硼膜 引导组织再生 

分 类 号：TQ460.1[化学工程—制药化工]