TCT法与塑料刷取样涂片法应用于宫颈病变筛查的对比研究  

A contrastive study on TCT and method of drawing materials and smearing with plastic brush in cervical disease screening

作　　者：林璇 姚静 王姽 

机构地区：[1]湖北省武汉市江岸区妇幼保健所,430017

出　　处：《中国实用医药》2008年第16期45-46,共2页China Practical Medicine

摘　　要：目的对比TCT法与塑料刷取样涂片法在宫颈病变筛查中的作用,以期找到适用于基层医院宫颈癌早期筛查的方法。方法2006年11月至2007年10月,对在武汉市江岸区妇幼保健所进行妇科普查的妇女分别以液基细胞检查(TCT)法(844例)和塑料刷取样涂片法(1000例)结合TBS分级系统进行宫颈病变的检测。结果TCT法、塑料刷取样涂片法制片的标本满意度分别为96.68%、94.20%,两组结果差异有统计学意义(P<0.05)。两组上皮细胞内病变患病率分别为6.52%、8.30%,两组结果差异无统计学意义(P>0.05)。接受度方面,家庭月收入在1000元以下者,对塑料刷采样涂片法的接受程度明显大于TCT法。结论TCT法与塑料刷取样涂片法应用于宫颈病变的筛查敏感性、特异性均高,但塑料刷取样涂片法操作简单,费用较低,适用于基层医院。Objective The aims of the study were to find out an applicable way for cervical disease screening in communities by comparing the roles of TCT and method of drawing materials and smearing with plastic brush in the disease screening. Methods From November ：2006 to October ：2007,844 cases and 1 000 cases in our hospital were tested for cervical lesion by the method of drawing material and smearing cells with plastic brush and thinprep liquid-based cytology test（TCT） respectively. TBS-group system was applied intio the cell diagnosis. Results The result showed that the satisfactory rate of sample was 96. 68% and 94.2% respectively,and the difference is significant（ P 〈 0. 05 ）between the two groups. The positive rates are 6.5：2% and 8.3 % respectively,which shows no obvious difference （ P 〉 0.05 ）. Regarding the acceptance, those whose family income falls below 1 000 yuan tend to accept the method of drawing materials and smearing with plastic brush rather than TCT. Conclusion Both TCT and the method of drawing materials and smearing with plastic brush are competent in screening the cervical lesion. However, the latter seems more applicable for the community use due to its easy operation and low cost.

关 键 词：TCT法 塑料刷取样涂片法 TBS诊断 宫颈癌筛查 

分 类 号：R737.33[医药卫生—肿瘤]