多发性硬化患者的临床特点分析  

CLINICAL CHARACTERS OF PATIENTS WITH MULTIPLE SCLEROSIS

作　　者：连志云[1] 刘立斌[1] 周红雨[1] 

机构地区：[1]四川大学华西医院,成都610041

出　　处：《现代预防医学》2008年第11期2171-2173,共3页Modern Preventive Medicine

摘　　要：[目的]通过分析总结我院267例多发性硬化(MS)的临床资料,探寻MS的临床表现特点。[方法]从临床表现和影像学等方面对病例进行描述性分析。[结果]267例MS病例中,男110例,女157例;发病年龄5到70岁,平均40岁,小于15岁的早发型病例占4.5%;23.9%病例病前有诱发因素;77.5%病例呈急性或亚急性起病;首发症状以肢体无力、感觉障碍和视力减退最常见。本组头颅MRI以侧脑室周围、半卵圆中心、脑干等处多见。[结论]MS起病年龄与欧美相当,以急性或亚急性起病;病变多累及视神经;临床类型和病程与神经功能缺失程度相关。[Objective] To summarize the clinical features of 267 multiple sclerosis （MS） cases in West China Hospital of Sichuan University. [Methods] Descriptively studied was carried out from the aspects of clinical and imagine characteristics of 267 MS patients. [Results] Among 267 cases, there were 110 males and 157 females. Mean age of onset of MS patients was 40 years, with a range of 5 to 70 years. The premature type （ 〈 15 years old） of MS accounted for 4.5%,Before onset, 23.9% cases had causative factors.77.5% had acute and subacute courses of onset. Limb weakness, paresthesia and visual disturbance were the most common initial symptoms. With regard to MRI, it usually happened in the area near lateral ventricle, semiovale center, brain stem. [Conclusion] The onset age of multiple sclerosis in southwest of China is equal to western country. The course is shorter. Optic nerve is easy to be invasived. Clinical types and course of disease relate with missing degree of nerve function.

关 键 词：炎性脱髓鞘 多发性硬化 

分 类 号：R741[医药卫生—神经病学与精神病学]