直肠恶性间质瘤13例临床分析  

The Clinical Analysis of 13 Cases of Malignant Rectal Gastrointestinal Stromal Tumor

作　　者：李云峰[1] 夏翠峰[1] 董建华[1] 蔡欣怡[1] 沈焘[1] 

机构地区：[1]云南省肿瘤医院大肠癌研究中心,云南昆明650118

出　　处：《昆明医学院学报》2008年第3期100-102,共3页Journal of Kunming Medical College

摘　　要：目的探讨直肠恶性间质瘤的临床诊断和治疗.方法回顾分析云南省肿瘤医院大肠癌中心收治的13例直肠恶性间质瘤病人的临床资料.外科手术切除11例,其中行dixon术5例,miles术3例,经肛门局部切除2例,全盆腔脏器切除1例.1例放弃治疗出院,1例口服格列卫.结果12例获得随诊,平均随访25个月.1例7个月后死于肝转移,其余存活.结论外科手术切除是直肠恶性间质瘤的首选治疗方法,术前应根据CT、腔内超声,MRI等检查结果,经评估后采取不同的手术方法.对不能手术或术后出现肝转移者可使用分子靶向药物甲磺酸伊马替尼(格列卫)治疗.Objective To analyze the features of clinical diagnosis and treatment of malignant rectal gastrointestinal stromal tumor. Methods Clinical data of 13 cases of malignant rectal gastrointestinal stromal tumor admitted in the center of rectal tumor of Yunnan tumor hospital （from the July 2001 to June 2007） were analyzed retrospectively. Results 11 of the 13 cases underwent surgical resection （5 cases were treated by Dixon＇ s resection, 3 cases were treated by Mile＇ s resection, 2 cases were resected transanally, 1 case underwent total pelvic exenteration, 1 case was treated by imatinib mesylate （Glivec） and 1 case rejected treatment.12 cases were observed by following-up of average 25 months. 1 case was died of liver matstasis 7 months later, the other patients were survived. Conclusions Surgical resection is the best treament for malign stromal tumor, the choice of operation should depend on the result of CT, endouhrasonic which has liver matstasis or is not suitable for operation, imatinib mesylate （Glivec） may ant rectal gastrointestinal and MRI. For the patient be good choice.

关 键 词：直肠 恶性间质瘤 手术 

分 类 号：R735.37[医药卫生—肿瘤]