复方阿嗪米特肠溶片联合马来酸曲美布汀治疗功能性消化不良疗效观察  

Combined compound azintamide and trimebutine in treatment of functional dyspepsia

作　　者：饶珈琦[1] 

机构地区：[1]广东省人民医院消化内科,广州510080

出　　处：《中国医药》2008年第7期420-421,共2页China Medicine

摘　　要：目的观察复方阿嗪米特肠溶片联合马来酸曲美布汀治疗功能性消化不良的的疗效。方法104例功能性消化不良患者采用完全随机设计方法分成2组，观察组54例，给予复方阿嗪米特肠溶片100mg，3次／d，餐后服用；马来酸曲美布汀100mg，3次／d，餐前服用。对照组50例，单用复方阿嗪米特肠溶片100mg，3次／d，餐后服用，疗程均2周。观察治疗前、后，饭后腹胀及腹部不适症状改善情况、食欲改善时间及复诊率。结果2组腹胀症状及改善食欲方面无统计学意义，饭后腹部不适症状观察组较对照组改善明显，并能降低复诊率。治疗过程中2组均无药物不良反应出现。结论复方阿嗪米特肠溶片和马来酸曲美布汀联合应用，治疗消化不良患者疗效明显，药物不良反应少，既安全又有效。Objective To observe the effect of combined compound azintamide and trimebutine on functional dyspepsia （FD）. Methods One hundred and four FD patients were randomly divided into two groups, The observation group （ n = 54 ） were given both compound azintamid and trimebutine and the control group （ n = 50） were only given compound azintamide. Clinical symptoms in both groups were recorded for comparison, Results There was no significant difference between two groups in abdominal fullness and improving appetites, but the combined therapy could significantly reduce the frequency of further medical consultation. There were no side effects in any patients during therapy. Conclusion Combined compound azintamide and trimebutine is an optimistic therapy in FD patients with the symptoms of upper and lower abdominal upset.

关 键 词：功能性消化不良 复方阿嗪米特 马来酸曲关布汀 

分 类 号：R57[医药卫生—消化系统]