交替化疗方案治疗转移性结直肠癌  

Alternating chemotherapy for metastatic colorectal cancer

作　　者：杨宇辉(综述)[1] 杨建伟(审校)[1] 

机构地区：[1]福建中医学院研究生部福建省肿瘤医院消化内科,福州350014

出　　处：《国际肿瘤学杂志》2008年第5期378-381,共4页Journal of International Oncology

摘　　要：以氟尿嘧啶、奥沙利铂、伊立替康为基础的化疗是转移性结直肠癌的主要治疗方法。近年来许多研究探讨了这些不同活性药物之间的联合应用，并进行了多种联合治疗模式的尝试。多项临床试验表明，交替方案化疗有效率高且毒性较低，为转移性结直肠癌的联合化疗拓展了新的领域。Fluorouracil,oxaliplatin and irinotecan are generally accepted as the standard chemotherapeutic agents for metastatic colorectal cancer. In recent years, the research advances on metastatic colorectal cancer treatment focus on the combination between different active drugs, and try to search advisable combined therapy methods. Clinical trials suggest that alternating regimen is effective and has lower toxicity which provides platform for further study of combined chemotherapy for metastatic colorectal cancer.

关 键 词：结直肠肿瘤 药物疗法 联合 

分 类 号：R730.53[医药卫生—肿瘤] R735.3[医药卫生—临床医学]