还原型谷胱甘肽治疗酒精性肝病疗效观察  

Clinical Syudy of Glutathione in Patients with Alcoholic Liver Disease

作　　者：周红萍[1] 罗晓燕[1] 茹仁萍[1] 

机构地区：[1]杭州市第六人民医院,310014

出　　处：《医学研究杂志》2008年第6期86-88,共3页Journal of Medical Research

摘　　要：目的探讨还原型谷光甘肽治疗酒精性肝病的临床疗效与安全性。方法将酒精性肝病患者75例分成治疗组(39例)和对照组(36例),两组均给予肝力新、门冬氨酸镁钾注射液、多种维生素等综合治疗,治疗组在综合治疗的基础上加用还原型谷光甘肽。观察两组治疗前后临床表现、肝功能变化。结果治疗组显效率43.6%,有效率51.3%,总有效率94.9%;对照组显效率19.4%,有效率58.3%,总有效率78.7%。两组总有效率比较有统计学差异(P<0.05)。结论还原型谷胱甘肽治疗酒精性肝病能改善临床症状、恢复肝功能而且安全。Objective To approach the clinical effect and safety of glutathione in patients with alcoholic liver disease（ ALD）. Method The patients were divided into two groups, including the control group and treatment group. Two groups are all treated with routine therapy such as Ganlixin,potassium magnesium aspartate, mulivitamins and so on, the treatment group add glutathione, to inspect clinical menifetation and liver function changes of two groups before and after treatments. Result Among the treatment group,43.6% showed notable effective result,51.3% effective,the total dffective rate is 94.9%. Among the control group, 19.4% showed notable effective result, 58.3% effective,the total dffective rate is 78.7%. There is a significant different between the two groups （ P 〈 0.05 ）. Conclusion Glutathione is effective and safety in the treatment of ALD on the prophase.

关 键 词：还原型谷胱甘肽 酒精性肝病 疗效 

分 类 号：R575[医药卫生—消化系统] R735[医药卫生—内科学]