16层螺旋CT灌注成像对原发性肝癌血流动力学的研究  

Study on Tumor Perfusion in Hepatic Carcinoma with 16-slice Helical CT

作　　者：陈光斌[1] 邹文远[1] 蔡庆和[2] 张自力[1] 石思李[1] 张桂华[1] 顾永丽[1] 

机构地区：[1]郧阳医学院附属人民医院放射科,湖北442000 [2]郧阳医学院附属人民医院肝胆外科,湖北442000

出　　处：《放射学实践》2008年第6期640-642,共3页Radiologic Practice

基　　金：湖北省教育厅科研项目(B200524015)

摘　　要：目的:探讨16层螺旋CT灌注成像对原发性肝癌血供评价的应用价值。方法:对17例原发性肝癌行多层螺旋CT灌注成像扫描,分别算出肿瘤组织、瘤旁组织及正常肝组织肝血流量(HBF)、肝血容量(HBV)、平均通过时间(MTT)、毛细血管通透性(PS)、肝动脉供血分数(HAF)、肝动脉灌流量(HAP)、门静脉灌流量(PVP)。结果:肿瘤组织、瘤旁组织及正常组织灌注参数中HBF、MTT、HAF、HAP差异有显著性意义。结论:多层螺旋CT灌注成像技术对评价原发性肝癌血流动力学具有重要价值,其中HBF、MTT、HAF、HAP可用于定量评价肝癌血供情况。Objectives.To study the value of 16-slice spiral CT perfusion imaging to evaluate the blood supply of hepatoeellular carcionma （HCC）. Methods： 16-slice spiral CT hepatic perfusion scans were performed in 17 patients with HCC. In the HCC tissues, paracancerous tissues and normal liver tissues, H BF, HBV, MTT, PS, H AF, HAP and PVP were calculated. Results：There was significant difference in HBF, MTT, HAF and HAP among HCC tissues, paracancerous tissues and normal liver tissues. Conclusion： 16-slice spiral CT perfusion imaging technique may be a safe and effective method to evaluate the hemodynamics of HCC. HBF, MTT, HAF and HAP can be used to quantitatively estimate the blood supply of HCC.

关 键 词：灌注 肝肿瘤 血液动力学 体层摄影术 X线计算机 

分 类 号：R735.7[医药卫生—肿瘤]