输血前对献血员血清HBsAg、抗-HCV、抗-HIV、RPR再次复查的重要意义  

The Significance of Re-screening Blood Donors for Serum HBsAg, Anti-HCV, Anti-HIV Antibody and RPR Before Blood Donation

作　　者：赵海专[1] 毕红玲[1] 杨萍 

机构地区：[1]湖北省人民医院检验科,武汉430060

出　　处：《医学新知》1997年第4期154-156,共3页New Medicine

摘　　要：为了杜绝输血后感染多种疾病（如肝炎、艾滋病等），必须对血库供血者的血清进行输血前最后一次筛选。直接用ELISA方法检测供血者血清中HBsAg、HCV抗体、HIV抗体，用凝集试验检测血清中的RPR抗体。结果示：21980例血标本中，HBsAg阳性5例，阳性率0．28‰，HCV抗体阳性3例，阳性率0．14％，HIV抗体、快速血浆反应素试验（RPR）均为阴性，黄胆阳性5例（总胆红质＞24u／L），阳性率0．23％，ALT增高2例（ALT＞40u／L），阳性率0．091％。表明由于试剂误差和其它因素的影响，经过血站多次筛选的血还会出现假阴性。作为把好最后一道关的血库，有必要再次进行严格的筛选，确保血源万无一失，杜绝输血后多种疾病的发生。To prevent posttransfusional hepatitis, it is of great significance to screen blood donors for serum HBsAg, anti-HCV, anti-HIV antibodies before they donate blood. To convince this, we screened blood donors for serum HBsAg, anti-HCV, antiHIV antibodies by ELISA and anti-RPR antibody by agglutination test. The results show that: in 21 980 donors, 5 are HBsAg postive (0. 28‰), 3 are anti-HCV antibodies positive (0. 14‰), 5 have jaundice (Total bilirubin>24 u/L; 0. 23‰), 2 have increased ALT (ALT>40 u/L; 0. 091‰). No donor is anti-HIV or RPR positive. This result indicated that although the donors have been screened for several times, there are false negative hepatitis because of the influene of reagent and other factors. Therefore,in order to prevent posttransfusional hepatitis. It is necessary for the blood bank, as the last assurer of blood quality, to rescreen the blood donor strictly before blood donation.

关 键 词：输血后肝炎 抗-HCV RPR 病毒性肝炎 艾滋病 

分 类 号：R512.601[医药卫生—内科学] R512.910.1[医药卫生—临床医学]