阿莫西林加甲硝唑治疗单纯性牙周炎30例  

Clinical observation of amoxicillin and metronidazoe in the treatment of chronic periodontitis

作　　者：闫志刚 

机构地区：[1]山西省阳曲县口腔门诊部

出　　处：《中国中医药现代远程教育》2008年第7期676-677,共2页Chinese Medicine Modern Distance Education of China

摘　　要：目的观察阿莫西林加甲硝唑治疗单纯牙周炎的临床疗效。方法选择临床诊断为单纯性牙周炎的患者30例共76颗患牙，随机分为局部机械治疗对照组和用阿莫西林加甲硝唑的实验组，记录基线、用药后1周、4周及8周的牙龈指数（GI）、牙周探诊深度（PD）和探诊出血（BOP）的变化并进行统计学分析。结果实验组和对照组在基线时各临床指标差异无显著性意义（P〉0．05），治疗后两组患牙各临床指标较用药前有明显改善（P〈0．05），而且两组间各时段差异也有统计学意义。结论阿莫西林加甲硝唑是治疗单纯性牙周炎有效、安全的治疗药物。Abstract Objective To evaluate the clinical effect of amoxicillin and metronidazoe in the treatment of chronic periodontitis. Methods：76teeth from 30patients suffering from periodontits were selected. The 30 patients were randomly divided into test group and control group, following initial therapy.amoxicillin and metronidazoe was applied to the teeth in the test group at baseline and 1 to 4 weeks, but the control group received no drug. The clinical indices including gingival index（GI）, probing depth（PD）,bleding on probing（BOP）and response to the ointments were evaluated at baseline, and 1.4.8 weeks after treatment, Results：At the baseline, there was no significant difference in the indices between the two groups（P〉0. 05） ,After treatment, both groups showed improvement in their examined indices（P〈0. 05, while there was significant difference betweenthe two groups （ P〈0. 05. Conclusion：Periocline was effective and secure local delivery drug for treating periodontits,

关 键 词：牙周炎 阿莫西林 甲硝唑 中医口腔医学 

分 类 号：R781.4[医药卫生—口腔医学]