浅述P物质与胰腺疾病  

Substance P and pancreatic diseases

作　　者：李静[1] 陆杰[1] 

机构地区：[1]重庆医科大学基础医学院生理学研究室,重庆400016

出　　处：《国际病理科学与临床杂志》2008年第3期252-256,共5页Journal of International Pathology and Clinical Medicine

摘　　要：P物质是一种脑肠肽,它广泛地分布在中枢神经系统和外周组织器官,在不同的部位发挥不同的生物学效应。在中枢它作为神经递质发挥作用且与痛觉传导有关,在外周神经它作为诱导神经源炎症的物质发挥作用。近年来发现P物质与胰腺的疾病如胰腺炎、糖尿病和胰腺癌关系密切。Substance P （SP） is a kind of brain-gut peptide. It distributes extensively in the central nervous system and peripheral tissue and organs. SP plays different biological effects in different parts. As a neuropeptide it plays role and conducts the senses of pain in the central nervous system, as well as inducts neurogenic inflammation in the peripheral nervous system. Recently,it was found that SP was associated with pancreatic diseases, such as acute pancreatitis, diabetes and diabetic complications and pancreatic cancer.

关 键 词：P物质 急性胰腺炎 糖尿病 糖尿病并发症 胰腺癌 

分 类 号：R576[医药卫生—消化系统]