眼眶副神经节瘤的临床分析  

Clinical analysis of primary paraganglioma of the orbit

作　　者：林婷婷[1] 何彦津[1] 张志华[1] 朱利民[1] 

机构地区：[1]天津医科大学第二医院眼科,天津市眼眶病研究所,天津300211

出　　处：《中国实用眼科杂志》2008年第6期616-619,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的分析眼眶副神经节瘤患者的病史、临床表现、影像学检查和治疗方法，为其诊断和治疗提供一定帮助。方法对眼眶副神经节瘤患者的临床资料进行回顾性分析。结果本组6例患者平均就诊年龄18．5岁，均因眼球突出就诊，病变渐进性发展，就诊时已有不同程度眼球运动受限、视力下降；影像学检查有较一致性改变，B超示病变边界清楚，内回声中等或缺乏，CDI示病变内部血流丰富，CT示病变密度大致中等，均匀或不均匀，强化明显，常伴有骨破坏，MRI示T1、T2均呈中信号；术中发现肿瘤呈灰红色或灰白色，可有或无包膜，证实CT所示的邻近眶骨破坏存在；手术治疗尽可能完整切除肿瘤，术后早期辅以局部放疗和化疗预防复发。结论眼眶副神经节瘤的临床表现，影像学表现具有一定特征性，对于辅助诊断具有重要价值，治疗方案的确定应结合肿瘤的生物学行为，综合治疗对改善预后具有重要意义。Objective To present some instruction in diagnosis and therapy of the orbital primary paraganglioma by analyzing the clinical manifestation, imaging appearance and treatment. Method The clinical data for 6 cases with orbital primary paraganglioma treated during 1986 to 2007 were analyzed retrospectively. Results The average visit age is 18.5 years. All the cases are admitted for gradually protopsis. Imaging characteristic had their consistency. On B-ultrasonography, tumor appeared as a lesion with moderate to scarce reflection, regular shape and clear boundary. CDI showed abundant bloodstream signal. CT showed lesions with moderate density, strong intensification and frequently accompanied with osteoclasia. On MRI, tumor appeared isointense on both T-1 and T-2-weighted scan. It can be seen in operation that the tumor is gray or gray-red with amicula or not. Completely excise the tumor assisted with radiotherapy and chemotherapy can prevent recrudescence. Conclusions There are some worthy features about the clinical manifestation and image examination, which playing an important role in auxiliary diagnosis of orbital primary paraganglioma.The formulation of therapeutic regimen is according to the biological behaviour of the tumors. The combined therapy is better to prognosis.

关 键 词：副神经节瘤 眼眶 眼部表现 影像学 治疗 

分 类 号：R739.4[医药卫生—肿瘤] R777.5[医药卫生—临床医学]