58例脊髓髓内室管膜瘤临床与预后  

Analysis on clinical and prognostic factors about 58 cases of intramedullary spinal cord ependymoma

作　　者：韩波[1] 袁葛[1] 王贵怀[1] 

机构地区：[1]首都医科大学附属天坛医院神经外科,北京100050

出　　处：《临床神经外科杂志》2008年第2期64-66,共3页Journal of Clinical Neurosurgery

摘　　要：目的回顾分析脊髓髓内室管膜瘤的诊疗特点和影响预后的因素。方法总结58例经手术治疗的脊髓髓内室管膜瘤患者的临床资料。结果MRI可以明确诊断,显微神经外科手术治疗使得大多数的脊髓室管膜瘤可以被全切。力弱,麻木、感觉迟钝和过敏,疼痛,膀胱直肠功能障碍是临床主要表现,而术后这四项症状都相应改善。结论早期手术是治疗脊髓室管膜瘤最有效的方法,术中超声波和电生理监测,椎板复位能够提高手术疗效。放疗、化疗则作为不能全切肿瘤时的辅助治疗来提高生活质量。Objective To summarize the features about diagnosis, treatment and effective factors to prognosis of intramedullary spinal cord ependymoma. Methods Clinical data of 58 cases with intramedullary spinal cord ependymoma treated by mierosurgical management were analyzed. Results Intramedullary spinal cord ependymoma can be clearly diagnosed through MRI and can be completely removed in most patients by microneurosurgery technique. Weakness, paresthesia and numbness, pain, dysfunction of urinary bladder or rectum are main clinical appearance. Conclusions Early surgical management is the most effective treatment on intramedullary spinal cord ependymoma. Intraoperative sonography, intraoperative neuro-electrophysiological monitoring and reconstruction of the laminar roof enhance the prognosis after the operation. Postoperative radiotherapy and chemotherapy improves quality of life as the assistantly managements.

关 键 词：脊髓髓内室管膜瘤 显微外科 预后 

分 类 号：R744.2[医药卫生—神经病学与精神病学]