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作 者:晏仲舒[1]
机构地区:[1]湖南医科大学湘雅医院外科
出 处:《中华普通外科杂志》1997年第4期253-254,共2页Chinese Journal of General Surgery
摘 要:家族性腺癌性息肉病(FAP)为一种常染色体显性遗传病,如不手术治疗终将发生癌变。现已公认本病的最佳术式为全大肠切除,直肠粘膜剥除,回肠造袋肛门吻合术。作者近9年内施行此手术11例。患者年龄为19~65岁。5例在30岁以内。平均随访1~9年,效果满意。除2例切口感染外无其它并发症。每日大便4~6次,能恢复工作。手术时5例已有恶变,其中1例有单个肝转移灶同时行局部切除。手术要点为:肌鞘宜短,充分止血并放置引流,无张力吻合,保护性回肠造口。作者认为除直肠内仅少数息肉,患者能坚持随访者外,均宜采用本术式。It has been established that the best surgical treatment of familial adenomatous polyposis(FAP)is total colectomy,rectal mucosa removal and ileo-anal anastomosis with pouch formation.Eleven cases,age ranging from 19 to 65 including five young patients of less than 30 years old,were treated. Bowel movements were 4-6 per day and patients could resume their work.Five patients were found with malignant change during the operation,and one had a solitary deposit in the liver which was locally resected.The lieal pouches were constructed as J type in ten and S type in one.There was no major morbidity except mild wound infection in 2 cases.Short segment of rectal muscular sheath, tension free pull-through anastomosis,protective ileostomy,which was closed three months later,and effective drainage of the rectal sheath were imperative for the success of the procedure.
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