不同病变的前列腺特异性抗原临床分析  

The clinical analysis of prostatic specific antigen

作　　者：南勋义[1] 党建功[1] 杨志尚[1] 张秉鸿[1] 胡国英[2] 贾爱琳[2] 欧阳艳[2] 

机构地区：[1]西安医科大学附属第一医院泌尿外科,710061 [2]西安医科大学附属第一医院核医学教研室,710061

出　　处：《临床泌尿外科杂志》1997年第5期272-274,共3页Journal of Clinical Urology

摘　　要：采用双抗体放射免疫法先后检测275例不同病变患者血清前列腺特异性抗原（PSA），其中前列腺癌（PCa）20例，18例阳性，2例＜4ng／ml，假阴性率10％；良性前列腺增生症（BPH）125例．其中25例PSA＞10ng／ml；成年男件其它病变（肝、肺、胃以及胰腺、肾脏等癌和肝硬化、消化道出血等疾病）91例，其中87例＜6．15ng／ml，4例＞10ng／ml；健康体检男性35例，其PSA值均＜2．8ng／ml；女性慢性肝炎3例，其PSA值0．2～0．3ng／ml。认为动态定期检查血清PSA，对监测PCa有否复发和治疗效果等具有简单易行、灵敏度极高的优点，是一项有临床实用价值的监测指标。Between Nov 1993 to Oct 1995,275 cases serum prostate specific antigen (PSA) were measured with radio-immunologic method,among them of 20 cases prostate cancer (PCa) 18 were positive,the level of PSA of 2 cases were less than 4 ng/ml,of 152 cases benign prostatic hyperplasia (BPH) 25 were higher than 10 ng/ml,of 91 cases other disease (hepatar cancer,lung cancer, stomach cancer, pancrers cancer, kedney cancer, etc ) 87 were less than 6. 15 ng/ml, 4 were greater than 10 ng/ml,the levels of PSA in 35 cases nomal male were less than 2. 8 ng/ml' Our data showed dynamic measurement of PSA was simple, nonivasive, sensitive, pracitical method to monitoring relapse,prognosis of prostate cancer.

关 键 词：前列腺肿瘤 PSA 临床分析 良性 前列腺增生 

分 类 号：R737.25[医药卫生—肿瘤] R697.32[医药卫生—临床医学]