晚期肿瘤患者大量恶性胸腹水治疗的临床探讨  

Clinical Study on the Terminal Ascites Cancer

作　　者：彭义梅[1] 

机构地区：[1]湖北省肿瘤医院综合科

出　　处：《湖北医科大学学报》1997年第4期355-356,361,共3页

摘　　要：对５１例晚期肿瘤恶性胸腹水治疗进行了对照性研究，其中治疗组３０例，对照组２１例，全部病例临床为Ⅲ期，治疗组病人胸腹腔穿刺一次性抽出积液到不能引流出为止，然后腔内注射顺氯氨铂（ＰＤＤ）。对照组抽液及注射其他药物或未用任何治疗。治疗结果，治疗组有效率为８００％，对照组有效率为４２８％，两组对照有非常显著差异（Ｐ＜００１）。大量放胸腹水后ＰＤＤ大剂量腔内注射可使腔内容物置于高浓度药液中，充分利用ＰＤＤ对肿瘤细胞的杀伤作用，并可减少对全身的毒性反应。提高晚期病人的生活质量，为下一步对原发灶的诊疗创造条件。This paper comparatively analyses the therapy for 51 cases of the terminal ascites cancer, which are all at stage IV And all the cases are divided into two groups. One group has 30 cases, in which the patients are tapped a great deal of fluid from the chest cavity and abdomen, and then given an injection of PDD; while the other group has 21 cases,in which the patients are tapped some fluid as well, but then given an injection of other medicine or no treatment at all. The results of the two groups are distinctively different. The effectual rate of the first group is 80.1% and the effectual rate of the second group is 42.8%( P <0.01). The therapy that tapping a great deal of fluid from the chest cavity and abdomen and then using a plenty of PDD is verified in the clinical application that it can kill and wound the tumor and decrease the toxicity reaction. The results also indicate that this therapy could help the patients to improve their living quality and could create a foundation for the next treatment of the primary affection.

关 键 词：肿瘤 顺氯氢铂 晚期 胸腹水 治疗 

分 类 号：R730.5[医药卫生—肿瘤] R442.5[医药卫生—临床医学]