椭圆偏振术在生物分子芯片研究中的应用  

Applications of Ellipsometry in the Investigations of Biomolecule Chips

作　　者：宋致堂[1] 李国华[1] 张霞[1] 孔凡美[1] 宋师霞[1] 

机构地区：[1]曲阜师范大学激光研究所,山东省曲阜市273165

出　　处：《曲阜师范大学学报（自然科学版）》2008年第3期59-62,共4页Journal of Qufu Normal University(Natural Science)

摘　　要：介绍了利用椭圆偏振测量仪原理测试生物芯片的检测方法.其最大优点在于测量过程不破坏被测体系,样品需要量少,操作简单,而且灵敏度高,可反映接近原子尺寸的变化,又能原位、实时跟踪检测表面膜的变化情况.椭圆偏振术在生物医学领域有着广泛的应用.In this paper, we study the detecting methods for testing the biochip by using the theory of ellipsometer. Our methods have several main advantages as follows. Firstly, it shall not destroy the tested system in the process of testing and need less samples. Secondly, the manipulation of our method is simple with high sensitivity in such a way that, it can reflect the variations in the atom level and monitor the changes of surface film simultane- ously. Accordingly, it has widely applications in biomedicine of ellipsometric.

关 键 词：生物芯片 光学椭偏成像技术 椭圆偏振术 应用 

分 类 号：O436[机械工程—光学工程]