272例遗传咨询夫妇流产死胎畸胎分析  

Analysis on abortion stillbirth fetus and teratism of 272 genetic counseling patients

作　　者：林秀英[1] 冯丽华[1] 刘祥印[2] 张红国[2] 葛欣欣[2] Renna 刘睿智[2] 

机构地区：[1]吉林大学第一医院妇产科,吉林长春130021 [2]吉林大学白求恩医学院细胞生物学教研室

出　　处：《中国妇幼保健》2008年第10期1391-1393,共3页Maternal and Child Health Care of China

基　　金：吉林省计划委员会项目〔2004〕987

摘　　要：目的：探讨外周血染色体异常与流产、死胎、畸胎的关系。方法：对2001年5月~2007年4月到吉林大学特殊疾病检测站进行遗传咨询的272例患者进行外周血淋巴细胞培养,进行染色体核型分析。结果：272例生育异常患者共检出与流产、死胎、畸胎相关的异常核型22例,包括女性染色体异常5例,男性染色体异常17例。结论：染色体核型异常是导致流产、死胎、畸胎的重要原因之一,且男性多于女性,夫妇双方都应当进行细胞遗传学染色体检查,有助于生育指导。To study the relationships between abnormal karyotypes of the patient＇s peripheral blood and the abortion, stillbirth fetus and teratism. Methods： By investigate 272 outpatients with genetic counseling in detection station of special disease, Jilin University from May 1, 2004 to April 30, 2007. Their peripheral lymphocytes were cultured and the abnormal karyotypes were analyzed. Results： There were 22 cases of abnormal karyotypes in 272 patients with genetic counseling. Of which, 5 cases were female abnormal karyotypes; 17 cases were male. Conclusion： The abnormal karyotype is one of important reasons which causes of the abortion, stillbirth fetus and teratism. Male is more than female. They can gain procreative instruction by investigate couple＇chromosome of cytogenetics＇methods.

关 键 词：染色体异常 核型 流产 死胎 畸胎 

分 类 号：R715[医药卫生—妇产科学]