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出 处:《现代预防医学》2008年第14期2749-2750,2767,共3页Modern Preventive Medicine
摘 要:[目的]探讨XE-2100全自动血液分析仪对影响血小板检测的参数警示信息的可信性。[方法]对2000例标本结果进行数据统计,根据仪器显示影响PLT检测的参数警示信息,确定手工镜检标本,将随机抽取218例无异常信息和有PLT警示信息的156例标本,按照警示信息Fragments、MICRO、LPLT、PLT Clumps?和PLT C(S)?分5组,作涂片经瑞氏染色镜检后分析,再将其XE-2100与手工镜检的PLT结果进行配对t检验。[结果]XE-2100对影响PLT检测的参数警示信息敏感度为100%,特异度为87.9%,阳性预测值为80.8%,阴性预测值为100%,准确度为91.9%;5组中XE-2100PLT警示信息与镜检符合率为42.1%~95.0%;Fragments、MICRO、LPLT组XE-2100与手工镜检PLT结果无统计学意义(P﹥0.05);PLT Clumps?、PLT C(S)?组结果差异有统计学意义(P﹤0.05;P﹤0.01)。[结论]XE-2100对Fragments、MICRO、LPLT和PLTC(S)?警示信息有较高的可信性,而对PLTClumps?警示信息准确性不理想,在实际工作中必须通过显微镜复检以保证检验结果的准确性。[Objective] To explore the reliability of the warning information parameter of platelet detection detected by the XE-2100 blood analyser. [Methods] A total of 2000 samples were analyzed. According to the wanting information parameter which impact on the detection of PLT indicated by blood analyzer, the specimen were detected with hand -made microscopic examination, 218 specimen without exception message and 156 specimen with warning information of PLT were randomly collected, these specimen were divided into five groups according to the warning information including Fregments, MICRO, LPLT, PLT clumps? and PLT c (s)?, then these smears were analyzed with microscopic after dyeing with Wright's staining. The results of PLT detected by XE-2100 and hand-made microscopic examination were analyzed by t test. [Results ] The sensitivity of the warning information parameter of PLT detection was 100%, the specificity was 87.9%, the positive predictive value was 80.8%, and the negative predictive value was 100% as well as the accuracy was 91.9%; In five groups, the coincidence rate of the abnormal message and the microcopic examination was at the range of 42.1%-95.0% ; The results of PLT in Fregments, MICRO and LPLT groups detected by XE-2100 did not showed significant difference when compared with the re- sults detected by hand-made microscopic examination (P 〉 0.05) ; The results showed significantly difference between PLT clumps? group and PLT C (S)? (P 〈 0.05; P 〈 0.01) group. [Conclusion] The analyzer has high reliability on the warning parameter of Fregments, MICRO, LPLT, and PLT C (S) , but the accuracy of warning information parameter for PLT clumps? is not favorable, therefore, the accuracy of the resut could be guaranteed by microscope in practical worl.
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