中药预防胆囊胆红素结石的研究  

Experimental Research on Prevention of Bilirubin Gallstone with Traditional Chinese Medicine Therapy

作　　者：郭绍举[1] 李健[1] 黄彬[1] 张竞超[1] 

机构地区：[1]深圳市中医院,广东深圳518033

出　　处：《中华中医药学刊》2008年第7期1519-1520,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：深圳市医学重点专科及科技计划项目(200204236)

摘　　要：目的:观察防石胶囊预防胆红素性胆囊结石的作用。方法:将48只豚鼠随机分成3组,空白组每天只喂养普通饲料,模型组每天喂胆红素结石诱石饲料,中药组喂胆红素诱石饲料及防石胶囊;计算胆囊结石发生率及胆汁中胆红素含量。结果:实验2个月后发现:胆红素胆囊结石发生率:模型组>中药组>空白组,胆汁中胆红素含量中药组与模型组相比有显著性差异。结论:防石胶囊能防止胆囊结石的复发。其机制可能和它们能降低胆汁中胆红素含量有关。Objective：To observe the effect of Fangshi capsule to prevent experimental Bilindain calculus of guinea pigs. Methods ：48 guinea pigs had been divided into 3 groups. The control group was fed with ordinary bait vessel ,the Bilirubin calculus group was fed with bait vessel of Bilirubin calculus derivation, the TCM therapy group was fed with bait vessel of Bilirubin calculus derivation and Fangshi capsules. The incidence rate of cholecystolithiasis and the cholerythrin in bile were detected. Results：Empirical study ：2 months past in the experimentation, the incidence rate of cholecystolithiasis and the cholerythrin in bile were arranged by turns in the empirical study of prevention from the formation of Bilirubin calculus ： the Bilirubin calculus group 〉 the TCM therapy group 〉 the control group. Conclusion ： The Fangshi capsules therapy can prevent the recidivation of cholecystolithiasis. The mechanisms perhaps is concerned with the therapy function of degrade the concentration of cholerythrin in bile.

关 键 词：防石胶囊 胆红素结石 结石复发 

分 类 号：R364.25[医药卫生—病理学]