手性试剂--(＋)-冰片基氯甲醚的合成  

Synthesis of (+)-bornyl chloromethylether as a chiral reagent

作　　者：汪浩[1] 王浦海[1] 严相平[1] 杭庆伟[2] 

机构地区：[1]南京工业大学江苏省药物研究所,江苏南京210009 [2]南京大学化学化工学院,江苏南京210008

出　　处：《化学试剂》2008年第7期535-536,共2页Chemical Reagents

摘　　要：以天然冰片为原料,与三聚甲醛、干燥氯化氢反应,制得标题化合物,产率约为70%。产物结构经元素分析、红外光谱、核磁共振谱等确证。（ ＋ ）-Bomyl chloromethylether as a chiral reagent was synthesized from （ ＋ ）-homyl alcohol by ehloromethylation in the presence of 1,3,5-trioxane and dry hydrochloride. The structure of the said was characterized by elemental analysis, IR, and ^1HNMR.The product yield was around 70% .

关 键 词：天然冰片 (+)-冰片基氯甲醚 手性试剂 合成 

分 类 号：R914[医药卫生—药物化学]