微波辐射下无溶剂催化合成葡萄糖五乙酸酯  

Solvent-free catalytic synthesis of glucose pentaacetate under microwave-irradiation

作　　者：廖晖[1] 陈连清[2] 周忠强[2] 

机构地区：[1]湖南环境生物学院,湖南衡阳421005 [2]中南民族大学化学与材料科学学院,湖北武汉430074

出　　处：《化学试剂》2008年第7期539-540,共2页Chemical Reagents

基　　金：国家自然科学基金资助项目(20702064);中南民族大学自然科学基金资助项目(YZZ07007)

摘　　要：首次在微波辐射下以硫酸氢钾为催化剂无溶剂合成了标题化合物,考察了微波辐射功率、微波辐射时间、原料配比、催化剂用量对产率的影响。最佳条件为:辐射功率为462 W,反应时间为8.0 min,葡萄糖与乙酸酐物质的量比为1∶7,硫酸氢钾用量为2.0%,产率可达89.5%。Glucose pentaacetate was synthesized at a solvent-free condition from glucose and acetic anhydride with potassium bisulfate used as the catalyst under microwave irradiation. The effects of microwave-irradiation power, microwave-irradiation time, reactants ratio, and amount of catalyst on the yield of glucose pentaacetate were studied. The results showed that the optimum reaction conditions were as follows： the microwave-irradiation power was 462 W, the reaction time was 8.0 min, the molar ratio of glucose and acetic anhydride was 1 ： 7, and the amount of potassium bisulfate was 2.0% ,with the yield reaching up to 89.5%.

关 键 词：微波辐射 合成 葡萄糖五乙酸酯 

分 类 号：O623.54[理学—有机化学]