前列腺癌发病与输精管结扎相关性的临床研究  

Clinical study of Long term effects of vasectomy on the incidence rate of prostate cancer

作　　者：聂勇[1] 刘昌荣[1] 郭贤坤[2] 颜克钧[1] 杜丹 高吴阳[4] 周天贵 张科[1] 李清 

机构地区：[1]宜昌市第一人民医院泌尿外科,湖北宜昌443000 [2]三峡大学医学院男科学研究所 [3]宜昌市第二人民医院泌尿外科 [4]三峡大学仁和医院泌尿外科 [5]宜昌市中心医院泌尿外科 [6]当阳市人民医院泌尿外科

出　　处：《临床泌尿外科杂志》2008年第6期424-427,共4页Journal of Clinical Urology

基　　金：宜昌市科技发展计划项目(编号:A06412)

摘　　要：目的：探讨前列腺癌发病与输精管结扎的相关性。方法：收集宜昌市6家医疗机构1996-2005年间收治的3186例60岁以上前列腺疾病（前列腺增生症，前列腺癌）住院患者，按是否接受输精管结扎分为结扎组（979例）与未结扎组（2207例）进行回顾性研究，按年龄分层分析统计两组中经病理学检查确诊的前列腺癌患者的发病率并比较其差异。结果：结扎组（60-、65-、70-、75-岁年龄组）前列腺癌的发病率显著低于未结扎组。结论：前列腺癌的发病率与输精管结扎有关，输精管结扎可降低前列腺癌的发病率。Objective：To study the corelation of Long term effects of vasectomy on the incidence rate of prostate cancer（PCa）. Methods：In a survey of 3 186 cases of BPH and PCa in-patients with an age range of more than 60 years in six hospitals in Yichang from 1996 to 2005, all data were collected and the patients were randomly divided in two groups. The vasaligation group contained 979 patients who underwent operation more than 20 years ago. 2 207 patients （control group） did not undergo operation. The incidence rates of PCa between the two groups were compared and analyzed. Results： The incidence rates（group of 60-, 65-, 70-, 75-） of Pca in the vasaligation group were lower than that of the control group. Rather striking age-related differences were observed. Conclusions： Vasectomy can reduce the incidence rate of prostate cancer.

关 键 词：前列腺癌 输精管结扎术 发病率 相关性 

分 类 号：R737.25[医药卫生—肿瘤]