美沙酮维持治疗海洛因依赖者的生活质量及影响因素  

An analysis of quality of life and related factors of heroin addicts who received methadone maintenance treatment

作　　者：胡文生[1] 王达平[1] 黄雄 郑洪波[1] 赵振环[1] 邓河晃[1] 郑朝盾[1] 黎娟花[1] 徐健雄[1] 黄巧芳[1] 韦玉娇[1] 陈志兴[1] 

机构地区：[1]广州市精神病医院物质依赖科,广东广州510370

出　　处：《广东药学院学报》2008年第3期306-308,共3页Academic Journal of Guangdong College of Pharmacy

基　　金：广州市卫生局资助"阿片类物质滥用者社区药物维持治疗管理与干预模式研究"(2007-YB-098)

摘　　要：目的探讨美沙酮维持治疗海洛因依赖者的生活质量状况及其影响因素。方法采用药物成瘾者生命质量测定量表(QOLDA),自行设计的患者一般情况和药物滥用情况调查表对269例美沙酮维持治疗的海洛因依赖者进行评价。结果①无劳教者社会功能得分高于有劳教者,两组之间差异有显著性(分别为30.83±7.59,28.71±6.01,P<0.05);②无强戒者生活质量在QOLDA总分及4个维度上得分均高于有强戒依赖者,两组之间差异有显著性(P<0.05);③花费≤100元/d的患者生活质量在QOLDA总分及躯体功能、戒断症状及毒副作用维度上得分高于花费>100元/d者,两组之间差异有显著性(P<0.05);④强戒次数和自己治疗次数对QOLDA总分有显著影响。结论美沙酮维持治疗的海洛因依赖者生活质量与劳教次数、强戒次数和每天花费等因素相关,患者的强戒次数和自己治疗次数对其生活质量有显著影响。Objective To explore quality of life and related factors in heroin addicts of methadone maintenance treatment. Methods 266 heroin addicts receiving methadone maintenance treatment were assessed by using quality of life scale for drug addicts （QOL-DA） ; selfdesigned common data and drug abuse investigation scale etc. Results （1）The scores of SO was significantly different between the patients who had experienced labor education and those without labor education（ P 〈 0.05 ）. （2）Total scores of QOL-DA, PH, PS, SO and ST showed significant difference between the patients who had already received compulsory detoxification and those without compulsory detoxification （ P 〈 0.05 ）. （3）Total scores of QOL-DA, PH, and ST had significant difference between the patients who spend less than or up to 100 RMB Yuan and those with spending exceeding 100 RMB Yuan in heroin addition everyday （P 〈 0.05 ）. （4） Frequency of compulsory detoxification and self-detoxification treatment had effects on the total scores of QOL-DA. Conclusion The quality of life in heroin addicts receiving methadone maintenance treatment was related to experiences of labor education, compulsory detoxification, and daily spending in heroin addition. Frequency of compulsory detoxification and self-detoxification treatment before abstinent period were important factors to the total scores of QOL-DA.

关 键 词：美沙酮 维持治疗 海洛因依赖 生活质量 

分 类 号：R749.64[医药卫生—神经病学与精神病学]