泪膜改变对Goldmann眼压测量值的影响  

Effect of Tear Film Changes on the Intraocular Pressure Measurement by Goldmann Applantion Tonometer

作　　者：曾阳发[1] 郭歆星[2] 林军[1] 曾祥云[3] 钟毅敏[1] 蔡小于[1] 刘杏[1] 

机构地区：[1]中山大学中山眼科中心,中山大学眼科学国家重点实验室,广州510060 [2]中山大学中山医学院,广州510080 [3]赣南医学院第一附属医院,赣州341000

出　　处：《眼科学报》2008年第1期27-29,61,共4页Eye Science

基　　金：广东省科技计划项目(2003C32725)

摘　　要：目的:探讨泪膜改变对Goldmann压平眼压计测量值的影响。方法:将68例(136只眼)受检者随机分为2组,每组34例。随机选择一只眼作为实验眼,另一只眼作为对照眼。A组的实验眼采用右旋糖苷70滴眼液滴眼,B组的实验眼采用粘弹剂Viscoat滴眼。采用Goldmann眼压计测量2次眼压,比较滴眼前、后测量值的差异。结果:A组对照眼第1、2次的眼压测量值分别为(14.44±2.68)mmHg(1mmHg=0.133KPa)、(14.47±2.69)mmHg,两次眼压测量值的差异无统计学意义(t=-0.329,P=0.744)。实验眼滴右旋糖苷70滴眼液前、后的眼压测量值分别为(14.41±2.63)mmHg、(12.94±2.59)mmHg,两次眼压测量值的差异有统计学意义(t=13.949,P=0.000)。B组对照眼第1、2次的眼压测量值分别为(14.29±2.96)mmHg、(14.35±3.12)mmHg,两次眼压测量值的差异无统计学意义(t=-0.466,P=0.644)。实验眼滴Viscoat前、后的眼压测量值分别为(14.53±3.13)mmHg、(11.18±3.07)mmHg,两次眼压测量值的差异有统计学意义(t=22.126,P=0.000)。两组的实验眼滴眼后的眼压均呈一致性的下降。结论:泪膜的改变可以使Goldmann压平眼压计的测量值产生偏差。Purpose： To explore the effect of tear film changes on the intraocular pressure （IOP） measurement by Goldmann applantion tonometer. Methods： Sixty-eight normal subjects were randomly divided into two groups （Gruop A and B）, 34 in each group. One eye of each subject by random selection was given Dextran （in Group A） and Viscoat （in Group B）, respectively. And the fellow eyes were used as controls. IOP was measured in all subjects twice using Goldmann applantion tonometer. And the difference between first and second measurements was compared. Result： In the control eyes of Group A, the average IOP of first and second measurements were （ 14.4d±2.68）mmHg （ 1 mmHg = 0.133 KPa） and （14.47±2.69）mmHg, there was no difference between the two measurements （t =-0.329, P= 0.744）. In eyes given Dextran, the average IOP of two measurements were （14.41±2.63）mmHg and （12.94±2.59）mmHg, there was significant difference between the two mea- surements （t = 13.949,P = 0.000）. In control eyes of Group B, the average IOP of first and second measurements were （14.53 ±3.13）mmHg and （11.18±3.07）mmHg, and there was no difference between the two measurements （t =-0.466, P= 0.644）. In eyes given Viscoat, the average IOP of two measurements were （14.53±3.13） mmHg and （11.18 ±3.07）mmHg, and there was significant difference between the two measurements （t = 22.126, P = 0.000）. After being given Dextran or Viscoat, the IOP values decreased consistently in both Group A and Group B. Conclusions ：The change of tear film components can affect IOP values by Goldmann applantion tonometer. Eye Science 2008; 24. 27-29.

关 键 词：眼压测量 眼压 泪膜 

分 类 号：R775[医药卫生—眼科]