正常人中央角膜厚度与Goldmann压平眼压的关系  

Effect of central corneal thickness on Goldmann applanation tonometer

作　　者：殷鸿波[1] 貟洪敏[1] 刘娅利[1] 余曼[1] 刘旭阳[1] 陈晓明[1] 

机构地区：[1]四川大学华西医院眼科四川大学华西医院眼科研究室,中国四川省成都市610041

出　　处：《国际眼科杂志》2008年第7期1375-1376,共2页International Eye Science

摘　　要：目的：了解正常人中央角膜厚度（central corneal thickness,CCT）的分布特点并探讨其与压平眼压测量值的关系。方法：采用光学角膜测厚仪及Goldmann压平眼压计检测169名正常人CCT和压平眼压。结果：169名受检者右眼平均CCT为0.547mm（95%可信区间0.443～0.651mm）,左眼0.551mm（95%可信区间0.453～0.649）。压平眼压右眼平均15.8mmHg,左眼15.5mmHg。CCT与年龄无相关关系,但与压平眼压测量值显著相关。线性回归分析表明,CCT每增加0.018mm,压平眼压增加1mmHg。结论：CCT变异是眼压测量误差的主要来源。CCT较厚的正常个体可表现“眼压增高”被误诊为高眼压症,而CCT偏薄的原发性开角型青光眼患者则可能因眼压测量“正常”被误诊为正常眼压性青光眼。在诊断青光眼或高眼压症时,特别是在眼压值与其他临床表现不符时,应考虑CCT有无变异。AIM： To study the distribution of central corneal thickness （CCT） in a suburb population and to determine the effect of CCT on the measurement of intraocular pressure （IOP）. METHODS： In this cross-sectional study, 169 normal subjects were evaluated. CCT was measured with an optical pachymeter by an observer, IOP was measured with Goldmann applanation tonometry by another observer using blind method. RESULTS： Mean CCT was 0. 547mm （95% confidence intervals 0. 543-0. 751 mm） in right eye and 0.551 mm （95% confidence intervals 0. 553-0. 749mm） in left eye. Mean IOP was 15.8mmHg in right eye and 15.5mmHg in left eye. There was no significant relationship between CCT and age, but a positive relationship was found between CCT and IOP. Linear regression analysis showed an increase of l mmHg in IOP with each 0,018ram increase in central corneal thickness. CONCLUSION： Variation in central corneal thickness is a significant source of variation in IOP measurement. Ocular hypertension can be misdiagnosed by pseudohypertension in the patients with thick CCT, and normal tension glaucoma can be misdiagnosed by primary openangle glaucoma in the patients with thin CCT. Pachymetry should be included in the diagnosis of glaucoma or ocular hypertension, particularly when IOP is inconsistent with other clinic data.

关 键 词：中央角膜厚度 Goldmann压平眼压 临床研究 治疗方法 

分 类 号：R775[医药卫生—眼科]