灯盏花素对肾上腺素模型小鼠降血糖作用的研究  

Studies on Hypoglycemic Action of Breviscapine in Adrenaline-induced Model Mice

作　　者：刘舒凌[1] 杨秀芬[1] 郭菁菁[1] 王乃平[1] 

机构地区：[1]广西中医学院药学院,广西南宁530001

出　　处：《时珍国医国药》2008年第5期1081-1082,共2页Lishizhen Medicine and Materia Medica Research

基　　金：广西教育厅资助课题项目[No.桂教科研(2004)20号]

摘　　要：目的观察灯盏花素对肾上腺素性高血糖的作用及机制。方法检测灯盏花素对肾上腺素模型小鼠血糖和NO含量的影响、对正常小鼠血糖的影响。结果灯盏花素对肾上腺素性高血糖有明显的降血糖效果、对血中NO水平有一定抑制作用,对正常小鼠血糖无明显影响。结论灯盏花素能对抗肾上腺素的升血糖作用。Objective To study the effect and mechanisms of breviscapine on hyperglycemia induced by adrenaline in mice. Methods To investigate the effect of breviscapine on the blood glucose level and NO content in adrenaline model mice, blood glucose level in normal mice. Results Breviscapine could significantly lower the blood glucose level in adrenaline model mice, had inhibitory effect on the increase of NO content, while had no hypoglycemic effect on the normal mice. Conclusion Breviscapine could antagonize Adrena line -induced rise of serum glucose level.

关 键 词：灯盏花素 肾上腺素模型小鼠 降血糖 

分 类 号：R285.5[医药卫生—中药学]