槲皮素-钼配合物的化学合成  

Chemical synthesis of quercetin and molybdenum complex

作　　者：阎素清[1] 柴保臣 贾小燕[1] 朱明君[1] 刘萍[1] 

机构地区：[1]郑州大学公共卫生学院卫生化学教研室,郑州450001 [2]深圳市宝安区石岩卫生监督所,深圳518108

出　　处：《郑州大学学报（医学版）》2008年第4期782-784,共3页Journal of Zhengzhou University(Medical Sciences)

摘　　要：目的:探讨槲皮素与钼的最佳反应条件,合成槲皮素-钼配合物。方法:以槲皮素和钼酸铵为原料,采用紫外分光光度法筛选反应液的最佳酸度、原料的物质的量比、温度、反应时间。结果与结论:槲皮素和钼酸铵在乙醇溶液中,以物质的量比1.5∶2.0(槲皮素∶钼),在pH值为2.5反应液中于20～30℃反应6h时,配合物合成产率最大。且经紫外、红外光谱测定推测出其结构。Aim ： To investigate the best conditions of the chemical reaction between quercentin and molybdenum to get quercetin-molybdenum complex. Methods：Quercetin and ammonium molybdate which served as raw materials reacted with each other under certain conditions to form the synthesis of quercetin-molybdenum. The synthesis＇ absorbance was detected by using UV spectruphotometric method to determine the reaction pH, the molar ratio of raw materials, reaction tempera- ture, and time. Results and conclusion：The synthesis of quercetin and ammonium molybdate has been tested to be at maximum yield when it was in ethanol solution for six hours, with the ratio of 1.5 ： 2.0 （ quercetin and ammonium molyb- date） , pH 2.5, the temperature at 20 to 30 ~C. The complex has been characterized by spectrum methods.

关 键 词：槲皮素 钼 化学合成 

分 类 号：R914[医药卫生—药物化学]