女性精神分裂症患者认知障碍与阴、阳性症状关系的探讨  

A study of the relationship between cognition deficit and positive symptoms,negative symptoms in female patients with schizophrenia

作　　者：张凯[1] 崔萌[1] 

机构地区：[1]陕西省西安市精神卫生中心,710061

出　　处：《精神医学杂志》2008年第4期248-249,共2页Journal of Psychiatry

摘　　要：目的研究女性精神分裂症患者认知障碍与阴、阳性症状群的关系。方法将新入院且未经治疗的女性精神分裂症患者按要求分为阳性症状群组(P组)和阴性症状群组(N组),并分别做韦氏记忆量表(WMS)和威斯康星卡片分类测验(WCST)检查。结果WMS检查显示,阳性症状群组明显优于阴性症状群组,有显著性差异,健康对照组理解因子显著优于阳性症状组,但其他各因子与阳性对照组无显著性差异。WCST检查阳性症状群组Rc、Re、Rpe三因子明显优于阴性症状群组,阳性症状群组和健康对照组无显著性差异。结论女性分裂症患者认知障碍与阴性症状群的关系明显较阳性症状群密切。Objective To study the relationship between cognition deficit and positive,negative symptoms in female patients with schizophrenia. Methods A total of 60 female patients with schizophrenia were divided into positive symptoms group （P group） and negative symptoms group （N group）. They were performed with WMS （Wechsler adult Memory Scale）and WCST（Wisconsin Card Sorting Test）. Results The score of WMS in P group was significantly higher than that of N group（P〈0.05）, the factor scores of WMS in control group were equal to those of P group （P〉0.05） except understanding factor. In WCST, the Rc, Re and Rpe scores of P group were significantly better than those of N group （P〈0. 05） ,and there had no significantly difference between P group and the normal control group（P〉0.05）. Conclusion In female patients with schizophrenia,cognition deficit has closer relation with negative symptoms.

关 键 词：女性 精神分裂症 认知障碍 阳性症状 阴性症状 

分 类 号：R749.3[医药卫生—神经病学与精神病学]