豚鼠不同部位引导的40Hz相关电位特点的对比  

Comparison between 40Hz potential from vertex and 40Hz potential from round window in guinea pigs

作　　者：刘淑芳[1] 付仲鹰[1] 史东光[1] 

机构地区：[1]吉林大学第一医院耳鼻咽喉-头颈外科,吉林长春130021

出　　处：《吉林大学学报（医学版）》2008年第4期621-623,共3页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅基金资助课题(990590)

摘　　要：目的：对比观察从豚鼠不同部位引导的40Hz相关电位的特点，为临床低频听力检测提供适宜指标。方法：采用适宜的参数即带通滤波为8-30Hz，刺激间隔为25ms，扫描时间为100ms从豚鼠的颅顶和圆窗同步记录听觉中潜伏期40Hz相关电位和听觉早潜伏期40Hz相关电位（40Hz AERP-MLR和40Hz AERP—ELR）。结果：两种电位的共同特点是频率响应好，波形稳定，易辨认。圆窗的40Hz AERP-ELR较颅顶的振幅高，反应阈值低，特别是低频的反应阈值低，在0．5kHz短纯音时听阈可达到（14．15±6．06）dBnHL。而颅顶40Hz AERP-MLR的反应阈值则是（43．50±9．65）dBn HL，明显高于圆窗反应阈值（P〈0．01）。结论：经圆窗引导的40Hz AERP—ELR在低频听力检测中优于颅顶，为临床低频听力检测提供一项较好的客观指标。Objective To compare the characteristics between two kinds of 40Hz auditory evoked potentials and provide suitable index for clinical auditory test of low-frequency. Methods The potentials including 40Hz auditory event related potential of middle latency response （40Hz AERP-MLR） and 40Hz auditory event related potential of early latency response （40Hz AERP-ELR） from window and vertex were recorded in guinea pigs. Results The common characteristics of the potentials were good frequency response, easy identification and lower responsive thresholds. Amplitude of 40Hz AERP-ELR was higher and threshold was lower than 40Hz AERP-MLR, especially 0.5kHz tone burst, which was （14.15±6.06） dBnHL. In vertex, the threshold of 40Hz AERP-MLR was （43.50±9.65） dBnHL, which was higher than that in round window （P〈0.01） . Conclusion 40Hz AERP- ELR recorded from round window is better than from vertex in low-frequency test. The experiment results indicate that the responses provide ideal index for clinical auditory test of low-frequency.

关 键 词：诱发电位 听觉 颅顶 圆窗 

分 类 号：R-332[医药卫生] R764.04