美沙酮维持治疗患者生存质量分析  

Quality of life for drug abusers accepting methadone maintenance treatment

作　　者：李杏莉[1] 谭红专[1] 孙振球[1] 张恒[1] 陈梦施[1] 欧秋英[2] 

机构地区：[1]中南大学公共卫生学院,长沙410078 [2]湖南省疾病预防控制中心,长沙410005

出　　处：《中南大学学报（医学版）》2008年第7期601-605,共5页Journal of Central South University ：Medical Science

基　　金：中国全球基金第四轮艾滋病项目(2008OR47)~~

摘　　要：目的:探讨接受美沙酮维持治疗后海洛因成瘾者生存质量改善情况,以及影响其改善的因素。方法:采用《生存质量简表(WHO-QOL BRIEF)》分别在患者入组治疗时、治疗后6个月随访调查,分析接受美沙酮维持治疗后以及不同特征患者生存质量改善情况。结果:接受治疗后患者生理领域、心理领域和生存质量总分上升明显;不同剂量的美沙酮维持治疗患者生存质量改善差异无统计学意义。男性以及吸毒年限长的患者接受治疗后生存质量改善明显。结论:社区美沙酮维持治疗能够提高海洛因成瘾者的生存质量。性别、吸毒年限是影响生存质量改善的可能因素。Objective To explore the change and influence factors of quality of life QOL for drug abusers who accepted methadone maintenance treatment （MMT）. Methods The questionnaire of QOL-BRIEF was used to measure the level of QQL when patients just entered the study and 6 months after the treatment respectively. The effect of therapy and characteristic of patients on change of QOL was analyzed. Results The scores in physiological domain, psychological domain, and the total score obviously increased after the treatment. There was no significant difference in the change of QOL between the patients of different dose groups. The QOLs of males and patients with long-time drug use improved significantly after the treatment. Conclusion MMT can raise the QOL of drug abusers. Gender and time of drug use may be the risk factors of QOL improvement.

关 键 词：药物依赖者 美沙酮维持治疗 生存质量 

分 类 号：R749.64[医药卫生—神经病学与精神病学]