卒中后抑郁患者认知功能和多导睡眠图对照研究  

Control study of cognitive function and polysomnogram in poststroke depression patients

作　　者：武小玉[1] 娄涛[1] 李冲[1] 宋景贵[1] 

机构地区：[1]新乡医学院第二附属医院,河南新乡453002

出　　处：《中国现代医学杂志》2008年第14期2033-2036,共4页China Journal of Modern Medicine

摘　　要：目的探讨卒中后抑郁(PSD)患者认知功能和睡眠特征。方法应用威斯康星卡片分类测验(WCST)和多导睡眠图检查对68例PSD和65例卒中后非抑郁患者进行测评,并与60例抑郁症和60例正常人比较。结果①WCST测试结果显示,PSD组、非抑郁组和抑郁症组与对照组比较各项指标差异均有显著性(P<0.01);PSD组与非抑郁组比较,除Nrpe外,其余指标差异均有显著性(P<0.01);PSD与抑郁症组比较,Re和Rpe两项差异有显著性(P<0.05～0.01)。②多导睡眠图结果显示,PSD组、非抑郁组和抑郁症组与对照组比较各项指标差异均有显著性(P<0.05～0.01);PSD组与非抑郁组比较睡眠潜伏期、深睡眠、觉醒次数、REM潜伏期、REM时间和密度差异均有显著性(P<0.05～0.01);PSD组与抑郁症组比较,除REM睡眠潜伏期无差异外,其余各项指标比较差异均有显著性(P<0.01)。结论PSD患者存在明显的认知功能障碍和睡眠障碍。[Objective] To explore the cognitive function and sleep features of poststroke depression（PSD） patients. [Methods] Measurements were conducted with the Wisconsin Card Sorting Test （WCST） and polysomnogram in 68 patients with PSD and 65 ones with poststroke non-depression （PSND） and compared with 60 ones with de- pression and 60 normals. [Results] （1）The WCST results showed that there were significances among the 4 groups（P 〈 0.01）, except Nrpe, there were high significances in the rest indexes＇ differences between the PSD and PSND group（P 〈 0.01）, there were significant differences in the Re and Rpe between the PSD and depression group （P 〈 0.05-0.01）. （2）The polysomnogram showed that there were significances among the 4 groups （P 〈0.05-0.01）, there were significant differences in sleep latency, deep sleep, awareness frequency, REM latency, REM duration and density between the PSD and PSND group （P 〈0.05-0.01）, except REM latency, there were high significances in the rest indexes differences between the PSD and depression group （P〈0.01）. [Conclusion] PSD patients have overt cognitive disturbane and sleep disorder.

关 键 词：脑卒中 卒中后抑郁 认知功能障碍 睡眠障碍 

分 类 号：R749.42[医药卫生—神经病学与精神病学]