PET-CT和MRI与螺旋CT对原发性肝癌病灶检出的对比观察  

Comparison with ^(18)F-FDG PET-CT,MRI and spiral CT in detection of primary liver carcinoma lesions

作　　者：郭明江[1] 陈龙华[1] 金吴东[1] 

机构地区：[1]南方医科大学南方医院放疗科,广东广州510515

出　　处：《中华肿瘤防治杂志》2008年第11期852-854,共3页Chinese Journal of Cancer Prevention and Treatment

基　　金：广东省科技计划项目基金(2004B30301011);广东省自然科学基金(2005004776)

摘　　要：目的:比较PET-CT、MRI与螺旋CT对肝癌病灶的检出差异,为肝癌放疗时确定靶区病灶积累影像学的比较资料。方法:回顾性分析诊断为原发性肝癌且治疗前进行了PET-CT、MRI与螺旋CT检查的病例共43例,比较3种检查方法对肝内及肝外病灶的检出情况。结果:在43例患者中,PET-CT检出了40例患者的127个肝内病灶及22例患者的137个肝外病灶;MRI检出了39例患者的114个肝内病灶及20例患者的103个肝外病灶;螺旋CT检出了35例患者的92个肝内病灶及14例患者的60个肝外病灶。其中PET-CT与螺旋CT比较,总病灶检出数(P<0.05)及肝内肝外病灶检出数(P均<0.001)差异有统计学意义;MRI与螺旋CT比较肝内外病灶检出数差异有统计学意义,P均<0.001;PET-CT与MRI比较中仅肝外病灶的检出数,差异有统计学意义,P<0.001。结论:对肝内外病灶的检出PET-CT与MRI均优于螺旋CT;PET-CT对转移灶的检出较有优势,对高分化肝细胞癌则MRI优于PET-CT;以CT模拟定位确定靶区制定放疗计划时,有针对性的运用MRI和PET-CT的影像资料,具有重要的参考价值。OBJECTIVE： To compare the differences of PET-CT, MRI and spiral CT in detection of primary liver carcinoma lesions so as to accumulate the comparative imaging information for target delineation in radiotherapy on liver cancer. METHODS： The data of 43 cases diagnosed primary liver cancer and inspected by PET-CT, MRI and spiral CT scan before treatment were collected retrospectively, and then the differences of the three methods in detecting intra-hepatic and extra-hepatic lesions were compared. RESULTS： In all the 43 cases, PET-CT detected 127 liver lesions in 40 cases, 22 of which were found 137 extra-hepatic lesions;MRI detected 114 liver lesions in 39 cases, 20 of which were found 103 extra-hepatic lesions. Spiral CT detected 92 hepatic lesions in 34 cases, 14 of which were found 60 extra-hepatic lesions. Statistical analysis： comparisons between PET-CT and spiral CT, total number of lesions （P〈 0.05）, extra-hepatic and intra-hepatic lesions （ all P hepati tween d0. 001）; comparisons between MRI and spiral CT, extrahepatic and intra-hepatie lesions （all P〈0. 001）; comparisons between PET-CT and MRI, extra-hepatic lesions （P 〈0.001） showed statistical significance. CONCLUSIONS, PET-CT shows advantages in detecting lesions. MRI shows the better capacity in detecting well-differentiated hepatocellular carcinoma lesions than PET-CT; they were better in detecting intrahepatic and extrahepatic lesions than spiral CT. It will be useful to refer to the result of lesions detected by PET-CT and MRI while to plan a radiotherapy treatment based on CT-simulation determining target.

关 键 词：肝肿瘤/诊断 磁共振戍像 X线体层摄影术 

分 类 号：R735.7[医药卫生—肿瘤]