复方斑蝥胶囊防治鼻咽癌面颈联合野急性放射反应的临床研究  

Study on Fufangbanmao capsules in preventing radiation injury in nasopharyngeal carcinomas

作　　者：周祖金[1] 刘少兵[1] 何思民[1] 

机构地区：[1]广西壮族自治区第二人民医院放疗科,桂林541002

出　　处：《中国肿瘤临床与康复》2008年第4期350-351,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的观察用中药减轻放射的急性反应的疗效。方法60例鼻咽癌随机分为治疗组和对照组,两组均予根治性放射治疗(先面颈联合野放疗),在放疗过程中,治疗组口服复方斑蝥胶囊配合放射治疗,对照组含漱朵贝液配合放射治疗。结果治疗组口腔、咽黏膜的急性放射损伤发生率为60.0%,对照组为93.3%(P<0.01);结束放疗时,治疗组原发灶残存率为13.3%,对照组为16.7%(P>0.05);治疗组口服复方斑蝥胶囊未见任何不良反应。结论复方斑蝥胶囊能明显减轻放疗引起的口腔、咽黏膜的急性放射损伤,提高患者的生存质量,且不降低放疗近期的疗效。Objective To study the efficacy of traditional Chinese medicine in the relief of acute radiation injury. Methods Sixty cases of nasopharyngeal carcinomas were divided randomly into 2 groups, treatment group and control group. Both of them were treated with radical radiotherapy（hyperfractionation）, with the former orally taking additional Fufangbanmao capsules and the latter gargling with Dobell＇s solution, Results The rates of buccal mucosa trauma in two groups were 60.0% and 93.3% respectively（ P 〈 0. 01 ） There was no adverse effect in treatment group. Conclusion Orally taking Fufangbanmao capsules can reduce acute radiation injury of huccal and pharyngeal mucosa and improve patient＇s life quality ,while does not reduce short-term curative effect of radiotherapy

关 键 词：鼻咽肿瘤 急性放射反应 复方斑蝥胶囊 

分 类 号：R739.63[医药卫生—肿瘤] R730.58[医药卫生—临床医学]