下颌骨副孔分布与安全手术切缘的相关性研究  

The relationship between accessory foramina on the medial and lateral mandibular surface and surgical margins

作　　者：王伯钧[1] 秦小云[2] 周思[3] 潘孟雄[3] 夏春波[3] 吴滨[1] 

机构地区：[1]柳州医学高等专科学校第一附属医院口腔科,广西柳州545002 [2]柳州医学高等专科学校,广西柳州545006 [3]桂林医学院解剖学教研室,广西桂林541004

出　　处：《中国临床解剖学杂志》2008年第4期451-454,共4页Chinese Journal of Clinical Anatomy

基　　金：广西科学技术厅自然基金项目(0542116)

摘　　要：目的:探讨下颌肿瘤及颌周恶性肿瘤经下颌骨副孔浸润传播的途径模式以及治疗下颌肿瘤及颌周恶性肿瘤时下颌骨合理的切除方式。方法:在10～20倍的体视显微镜下观察下颌骨副孔的数量及分布规律,并对26例下颌骨肿瘤病人采用适当的下颌骨手术切除方式。结果:下颌骨内侧面着色副孔的出现率比外侧面的多;在外侧面,下区上部的着色副孔数最多;在内侧面,下区中部的着色副孔数最多。临床手术26例,术后追踪随访23例,19例手术后局部未见肿瘤复发,5年生存率76.9%。结论:(1)下颌骨肿瘤、颌周恶性肿瘤对下颌骨的浸润蔓延与下颌骨副孔密切相关;(2)彻底阻断肿瘤可能经副孔传播的途径,对建立一个真正"安全"的外科手术切缘,对患者的局部复发率和预后的控制均起积极作用。Objective： To study the mode of which the oral tumor spread into the mandible and its relationship with the accessory foramina. Methods： Mandibles were divided into 2 regions and 6 sections in 60 specimens, and then the number and their distributions on the surface of mandible were observed under microscope. 26 patients with mandible tumor were performed by the method of mandiblectomy. Results： In each specimen, there were more foramina on the medial surface of the mandible than those on the lateral, and the inferior region more than the superior region. In the medial wall, the region around the inferior dental foramen was the commonest dedicated site for repeated the occurrence of the accessory foramina. 23 patients had no local relapse or metastasis during the follow-up period of 40.6 months. Conclusions： Accessory foramina on the medial and lateral mandibular surface is closely correlated with surgical margins.

关 键 词：下颌骨 副孔 口腔肿瘤 外科安全手术切缘 

分 类 号：R782[医药卫生—口腔医学] R616[医药卫生—临床医学]