上颌窦癌的治疗──254例临床分析  

Management of maxillary sinus carcinoma:Clinical analysis of 254 cases

作　　者：朱又华[1] 李奇志[1] 任庆荣[1] 孙学华[1] 

机构地区：[1]湖北省肿瘤医院头颈外科,武汉430070

出　　处：《耳鼻咽喉（头颈外科）》1997年第5期272-276,共5页Chinese Arch Otolaryngology-Head Neck Surg

摘　　要：回顾1975～1991年间收治的254例上颌窦癌患者在不同治疗情况下，包括放疗、化疗、手术，单纯或综合治疗下的局部控制和生存情况。病例随访5年或至死亡，失访者按死亡计。统计学方法用U检验。结果：本组总的局部控制率为59．1％，Ⅱ、Ⅲ、Ⅳ期分别为71．4％、60．5％和54.6％，以R＋S，A＋R＋S的局部控制率为最高，分别为80．0％和92．0％。治疗失败原因多为局部复发。总的3、5年生存率分别为44．1％，35．0％，Ⅱ、Ⅲ、Ⅳ期的5年生存率分别为53．6％、35．3％、30．9％。R＋S和A＋R＋S的5年生存率为54．0％、56．0％，较其它治疗方法为高。上颌窦癌的治疗以计划性的综合术前放、化疗加手术的疗效为最好，早期发现和局部控制是治疗成功的关键。To analyse the local control and survival ratesl as well as the reason of failure in treating maxillary sinus carcinoma, 254 cases treated between 1975 and 1991 were retro-spectively analysed. The treatment methods included radiotherapy, arterial chemothera-py and surgery, alone or combined. All patients were followed-up at least 5 years or un-til death. Our results showed that the total local control rate was 59. 1%, and in stages Ⅱ, Ⅲ, Ⅳ as 71. 4%, 60. 5% and 54. 6% respectively, and in groups R+S, A+R+S as 80. 0% and 92. 0%, higher than that in other groups. The main reason of failure was local recurrence. The total 5-year survival rate was 35. 0%, and in stages Ⅱ, Ⅲ, Ⅳ as 53. 6%, 35. 3% and 30. 9%, in groups R+S, A+R+S as 54. 0% and 56. 0%, higher than that in other groups. It was concluded that combined therapy was the treatment of choice for patients with maxillary sinus carcinoma. Early detection and local control were the key to success.

关 键 词：上颌窦肿瘤 癌 治疗 临床分析 

分 类 号：R739.620.5[医药卫生—肿瘤]