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作 者:李智勇[1] 葛莹[1] 刘静红[1] 王克礼[1] 伍建林[1]
机构地区:[1]大连医科大学附属第一医院放射科,辽宁大连116011
出 处:《大连医科大学学报》2008年第4期366-368,共3页Journal of Dalian Medical University
基 金:辽宁省教育厅青年基金(2005120)
摘 要:[目的]探讨胃肿瘤CT灌注成像的可行性,评价其在胃肿瘤性病变诊疗中的初步价值。[方法]对13例胃肿瘤患者进行了4排和16排CT灌注成像扫描。采用CT电影扫描技术对肿瘤中心层面进行灌注扫描,层厚10 mm/2 i;使用高压注射器经右肘前静脉快速团注造影剂,剂量45~50 mL,注射速度3.5~4.0 mL/s,扫描延迟时间5 s,扫描总时间45 s。利用胰腺模式进行CT灌注数据的处理,计算血流量(BF)、血容量(BV)、平均通过时间(MTT)以及表面渗透性(PS)。[结果]正常胃壁的BF、BV、MTT、PS分别为(357.24±212.44)mL/(min·100 g)、(16.53±9.78)mL/100 g、(4.29±3.12)s、(36.40±39.54 )mL/(min·100 g);胃肿瘤的则为(62.18±38.1)mL/(min·10 0 g)、(5.21±4.58)mL/100 g、(1 1.79±8.18)s、(13.09±12.62)mL/(min·100 g),P值 分别为0.0017、0.014、0.04和0.036。[结论]CT灌注成像可提供胃肿瘤的血流动力学信息,在 胃肿瘤的诊断中有一定价值,其临床应用前景广阔。[Objective] The purpose of this study is preliminarily to discuss perfusion imaging technique with Multi-slice CT and its clinical application value of diagnosis in stomach neoplasm.[Methods] Thirteen patients with known stomach neoplasm performed perfusion imaging with 4 or 16-slice CT.Performing perfusion imaging in central slice of neoplasm,using CT cine scan,slice thick 10 mm/2i;with high pressure syringe,injecting quickly from right elbow-front vein,dosage 45~50 mL,injection rate(3.5~4.0) mL/s,scanning delay time 5 s,scanning total time 45 s.We performed perfusion CT post-processing using pancreatic mode of Perfusion CT software.Blood flow(BF),blood volume(BV),mean transit time(MTT),and permeability surface(PS) of gastric wall were computed for every case.[Results] BF,BV,MTT and PS of normal gastric wall were(357.24±212.44) mL/(min·100 g),(16.53±9.78) mL/100 g,(4.29±3.12) s,(36.40±39.54) mL/(min·100 g);for gastric tumors were(62.18±38.1) mL/(min·100 g),(5.21±4.58) mL/100 g,(11.79±8.18) s,(13.09±12.62) mL/(min·100 g) respectively.The P values for perfusion CT parameters between gastric tumors and normal gastric wall were 0.0017,0.014,0.04 and 0.036,respectively.[Conclusion] Perfusion CT can provide hemodynamics of gastric tumors and play a key role in the diagnosis of gastric tumors.It's clinical application prospect will be fully broad.
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