注意缺陷多动障碍儿童药物治疗观察和停药原因分析  

Observation of drug treatment and analysis of the reasons for withdrawal in attention deficit-hyperactivity disorder

作　　者：张建娜[1] 王贺茹[1] 宋文红[1] 

机构地区：[1]首都儿科研究所,北京100020

出　　处：《中国儿童保健杂志》2008年第4期462-464,共3页Chinese Journal of Child Health Care

摘　　要：【目的】了解注意缺陷多动障碍（attention deficit-hyperactivity disorder，ADHD）患儿的药物治疗及部分患儿自行停药的原因。【方法】采用门诊登记统计和建病历随访，于2005年7月～2006年12月期间符合DSM—Ⅳ诊断标准的全部首次就诊ADHD儿童。疗效评定主要根据临床症状描述。【结果】门诊一年半首诊ADHD患儿共613人，接受药物治疗的共280人，其中190人采用中枢兴奋剂（哌甲酯）治疗。追访在哌甲酯治疗有效者中有25．8％因担心长期用药会影响生长发育以及一些症状较轻的儿童选择停药，还有6．8％认为治愈停药，家长认为治疗效果不满意停药者仅占6．3％。【结论】中枢兴奋剂治疗对改善ADHD核心症状确有明显疗效，家长担心副作用发生以及患儿症状轻是导致停药的主要原因。[Objective] To understand the efficacy of the drug treatment of attention deticit-hyperactivity disorder （ADHD） as well as the reasons for some patients＇ drug withdrawal. [ Methods] Outpatient registration statistics and follow-up visit after making clinical records were adopted. These children who were consistent with the diagnostic criteria of all DSM-Ⅳ from July 2005 to December 2006 were first diagnosed ADHD. The main therapeutic evaluations were according to the clinical manifastation. [Results] During the one year and a half research, the first diagnosed ADHD children were 613 in all, 280 of which accepted Chinese and Western medicine treatment, and 190 of which took central stimulants. Some people of the effective drug treatment group worried that those drugs would affect the long-term growth and some children were with less symptoms,25.8% disused within one year, while 6.8% stopped the treatment because of cure,and at the same time the withdrawal for the dissatisfaction from parents with the treatment only accounted 6.3 %. [ Conclusion] Drug treatment can significantly improve the main symptoms of ADHD,parents worrying about the side effects and some children with less symptoms are the key reasons leading to the withdrawal.

关 键 词：注意缺陷多动障碍 药物治疗 停药原因 

分 类 号：R749.94[医药卫生—神经病学与精神病学]