HER-2在乳腺癌中的研究进展  

Progression of HER-2 in breast cancer

作　　者：单涛[1] 盛薇[1] 李萌[1] 王虎霞[1] 

机构地区：[1]西安交通大学医学院第一附属医院普外科,西安710061

出　　处：《国际外科学杂志》2008年第8期556-558,共3页International Journal of Surgery

摘　　要：HER-2／neu基因又称c—erbB-2或erbB-2基因，是1985年确认的v—erbB-2相关的原癌基因。自从HER-2被发现与乳腺癌患者的预后不良密切相关以来，此方面的研究越来越多。现将乳腺癌中HER-2（HER-2／neu）相关知识综述如下。The HER-2/neu gene, also named e-erbB-2 or erbB-2, is proto-oneogene of v-erbB-2 which was firstly discovered in 1985. Many studies have been reported since that amplification of the HER-2 gene in breast tumors is associated with poor prognosis was recognized. The relevant knowledge of HER-2/neu gene is summarized in this article.

关 键 词：乳腺癌 HER-2 临床研究 治疗方法 

分 类 号：R737.9[医药卫生—肿瘤] R737.9[医药卫生—临床医学]